{"id":"W2024201682","doi":"10.1038/ng.422","title":"FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Fetal and Pediatric Neurological Disorders","field":"Medicine","cited_by":282,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute","keywords":"Biology; Hindbrain; Fourth ventricle; Anatomy; Cerebellar vermis; Hypoplasia; Brachyury; Locus (genetics); Cerebellum; Genetics; Mesoderm; Neuroscience; Embryo; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033633,0.0001859986,0.0002525458,0.00007665081,0.0001061047,0.00002432695,0.0000817914,0.0003668428,0.00007324501],"category_scores_gemma":[0.00007415664,0.000146571,0.00006525983,0.0001810678,0.00002114796,0.00004134659,0.00003735453,0.000241752,0.00003191416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002867842,"about_ca_system_score_gemma":0.00005782346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000100072,"about_ca_topic_score_gemma":0.000002039923,"domain_scores_codex":[0.9988247,0.00001071419,0.0002822848,0.0002839322,0.0002630153,0.0003353359],"domain_scores_gemma":[0.9993783,0.00003455965,0.00006415768,0.0001648712,0.0001435341,0.000214634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00745199,0.00141049,0.02989316,0.001466348,0.0004777307,0.0001397188,0.009382164,0.0000359499,0.04558903,0.0007015992,0.4529057,0.4505462],"study_design_scores_gemma":[0.004891649,0.002470044,0.1172322,0.00003230903,0.0001931212,0.00005404588,0.00004449684,0.0004459357,0.03997575,0.0007205503,0.8335016,0.0004382623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845615,0.003464458,0.0005312855,0.00933855,0.000196665,0.001046277,0.0001007845,0.00004569067,0.0007147772],"genre_scores_gemma":[0.9527179,0.0002671148,0.008466672,0.0370307,0.0003023974,0.00002432574,0.0001087378,0.00001492059,0.001067205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4501079,"threshold_uncertainty_score":0.5976993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072753340413161,"score_gpt":0.2583265379056859,"score_spread":0.2475990045015543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}