{"id":"W2024269966","doi":"10.1161/circulationaha.111.072561","title":"Efficacy and Safety of Celivarone, With Amiodarone as Calibrator, in Patients With an Implantable Cardioverter-Defibrillator for Prevention of Implantable Cardioverter-Defibrillator Interventions or Death","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences","funders":"Sanofi","keywords":"Medicine; Ventricular tachycardia; Ventricular fibrillation; Amiodarone; Implantable cardioverter-defibrillator; Internal medicine; Placebo; Cardiology; Clinical endpoint; Defibrillation; Ejection fraction; Sudden cardiac death; Hazard ratio; Randomized controlled trial; Atrial fibrillation; Heart failure; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001257544,0.0001780347,0.0004762974,0.00008409686,0.00004894797,0.0000115101,0.00007524765,0.0001145852,0.000002631431],"category_scores_gemma":[0.00001796315,0.0001448831,0.00009376014,0.0001166995,0.00005578561,0.00003607132,0.0000361504,0.00003089997,4.621399e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008504684,"about_ca_system_score_gemma":0.00008114598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002596517,"about_ca_topic_score_gemma":0.0001799249,"domain_scores_codex":[0.9988172,0.00007030737,0.0003877941,0.0003577556,0.0001590773,0.00020786],"domain_scores_gemma":[0.9992223,0.00001165395,0.0002229124,0.0003463296,0.0001209939,0.00007579251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01085835,0.0004790846,0.9699764,0.0005552174,0.0006658771,8.415681e-8,0.0003326006,0.0007403003,0.009017006,0.0006423726,0.0002428712,0.006489794],"study_design_scores_gemma":[0.007319293,0.002173048,0.9731351,0.000210606,0.0002815153,0.00001929732,0.0001342275,0.00003348054,0.01431143,0.0001688635,0.001891655,0.0003215485],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858873,0.0004686984,0.007656048,3.45912e-7,0.00005188784,0.000852842,0.0002029015,0.000007339094,0.004872611],"genre_scores_gemma":[0.9977524,0.00007214516,0.001611185,0.000007181302,0.00002503939,0.00002419387,0.0004515974,0.00002975263,0.00002651053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01186507,"threshold_uncertainty_score":0.590816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02165998526178166,"score_gpt":0.2548704569725015,"score_spread":0.2332104717107198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}