{"id":"W2024269966","doi":"10.1161/circulationaha.111.072561","title":"Efficacy and Safety of Celivarone, With Amiodarone as Calibrator, in Patients With an Implantable Cardioverter-Defibrillator for Prevention of Implantable Cardioverter-Defibrillator Interventions or Death","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences","funders":"Sanofi","keywords":"Medicine; Ventricular tachycardia; Ventricular fibrillation; Amiodarone; Implantable cardioverter-defibrillator; Internal medicine; Placebo; Cardiology; Clinical endpoint; Defibrillation; Ejection fraction; Sudden cardiac death; Hazard ratio; Randomized controlled trial; Atrial fibrillation; Heart failure; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001579809,0.0006180783,0.001294916,0.0003475832,0.0002214358,0.0006485352,0.0004026088,0.0009327031,0.001305145],"category_scores_gemma":[0.00245456,0.0003416582,0.001125618,0.0002379715,0.0007487932,0.0005998808,0.0002699554,0.001143392,0.0002175527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004290735,"about_ca_system_score_gemma":0.0005311572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002873862,"about_ca_topic_score_gemma":0.0004628823,"domain_scores_codex":[0.9990922,0.0004677761,0.0001126412,0.0001442286,0.00009616461,0.00008695607],"domain_scores_gemma":[0.9985814,0.0004789374,0.0004112901,0.00008908693,0.0000809923,0.0003583622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.908235,0.01674546,0.01671048,0.0004667509,0.001311939,0.0001199172,0.0001128947,0.0004554276,0.01433535,0.00006273592,0.0002726335,0.04117138],"study_design_scores_gemma":[0.5178624,0.4346025,0.04239625,0.00005140802,0.001202811,0.0001666122,0.0000511584,0.0007746972,0.002236319,0.00007606328,0.0005590881,0.00002073782],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970838,0.002154173,0.0001094865,0.00009864169,0.00005097386,0.0001476453,0.00006495781,0.00001050363,0.000279635],"genre_scores_gemma":[0.9986156,0.0005508804,0.0002330045,0.0001322779,0.00009759943,0.0001254835,0.0001109339,0.000001776752,0.0001323309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579809,"threshold_uncertainty_score":0.008354902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02165998526178166,"score_gpt":0.2548704569725015,"score_spread":0.2332104717107198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}