{"id":"W2024384770","doi":"10.1074/jbc.m111921200","title":"Protein Kinase C-βII Is an Apoptotic Lamin Kinase in Polyomavirus-transformed, Etoposide-treated pyF111 Rat Fibroblasts","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Etoposide; Cancer research; Apoptosis; Lamin; Kinase; Protein kinase A; Cell biology; Medicine; Biology; Internal medicine; Biochemistry; Nucleus; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128087,0.0004573127,0.0002349097,0.0002381951,0.0001914565,0.0003276646,0.0002205521,0.0002488486,0.001428372],"category_scores_gemma":[0.0001416828,0.0002059361,0.0002662529,0.0001710594,0.0002363027,0.0001913623,0.0001210974,0.000572515,0.0007636982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003912443,"about_ca_system_score_gemma":0.0002414898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134836,"about_ca_topic_score_gemma":0.0008712661,"domain_scores_codex":[0.9998567,0.00001541534,0.00001935377,0.00003675657,0.00003404352,0.00003770856],"domain_scores_gemma":[0.999846,0.00002535355,0.00004207663,0.00003137656,0.00001666591,0.00003844872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001183796,0.00001690016,0.0001925153,0.00001695256,0.000002223308,0.0000563214,0.00001318042,0.00002152393,0.9990681,0.00003308638,0.000009358502,0.0004513783],"study_design_scores_gemma":[0.00001411349,0.0002174298,0.00534015,0.000004543679,0.00000724979,0.0003694608,0.0000278221,0.0002546076,0.9927192,0.000022692,0.001019029,0.000003815434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960214,0.001147759,0.001232471,0.00004977217,0.0000241909,0.00001999793,0.0004118694,0.00004597224,0.001046518],"genre_scores_gemma":[0.992415,0.0009730058,0.001324115,0.00002967541,0.00001046522,0.00004882654,0.001073154,0.00002331679,0.004102552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001428372,"threshold_uncertainty_score":0.004778385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02873916302100137,"score_gpt":0.2640129876494433,"score_spread":0.2352738246284419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}