{"id":"W2024384954","doi":"10.1074/jbc.m001443200","title":"Tandem Repeats Are Involved in G1 Domain Inhibition of Versican Expression and Secretion and the G3 Domain Enhances Glycosaminoglycan Modification and Product Secretion via the Complement-binding Protein-like Motif","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Versican; Secretion; Glycosaminoglycan; Cell biology; Chemistry; Proteoglycan; ADAMTS; Tandem repeat; Metalloproteinase; Biochemistry; Biology; Matrix metalloproteinase; Thrombospondin; Gene; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007751725,0.0003800448,0.0001444581,0.00009131784,0.00009636808,0.0001767642,0.0001034215,0.0002190194,0.0006387886],"category_scores_gemma":[0.00008610988,0.0000997422,0.0002542104,0.0001002691,0.0002667153,0.0001097584,0.0001345733,0.0003376551,0.0002361772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003234507,"about_ca_system_score_gemma":0.0002113071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007194229,"about_ca_topic_score_gemma":0.001071858,"domain_scores_codex":[0.9999065,0.00001903318,0.000006230312,0.00001514749,0.00001829958,0.00003469046],"domain_scores_gemma":[0.9999261,0.0000156005,0.00002478117,0.000006743757,0.000003954606,0.00002281197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007413263,0.000007561023,0.00008674374,0.000009855002,0.000001813612,0.0000290559,0.000004309201,0.00003931451,0.9994654,0.00004941011,0.000007019301,0.0002255076],"study_design_scores_gemma":[0.00001784657,0.0001573296,0.00328655,0.000002455457,0.0000129277,0.0002041501,0.00001031744,0.0005461424,0.9950832,0.00003327638,0.0006431685,0.000002613698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987509,0.0003123927,0.0005152122,0.00002800565,0.000003506331,0.000006717017,0.00005086706,0.00001702733,0.0003154279],"genre_scores_gemma":[0.9978769,0.0002128383,0.0009144469,0.00002700223,0.000003028295,0.000009567832,0.0001377041,0.00000935903,0.0008092539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007194229,"threshold_uncertainty_score":0.002346754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02188419327219299,"score_gpt":0.2650444765563165,"score_spread":0.2431602832841235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}