{"id":"W2024396003","doi":"10.1371/journal.ppat.1000628","title":"The Leishmania donovani Lipophosphoglycan Excludes the Vesicular Proton-ATPase from Phagosomes by Impairing the Recruitment of Synaptotagmin V","year":2009,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Fonds Québécois de la Recherche sur la Nature et les Technologies; Armand-Frappier Foundation; Colorado State University","keywords":"Lipophosphoglycan; Phagosome; Leishmania donovani; Leishmania; Cell biology; Synaptotagmin 1; Chemistry; ATPase; Biology; Biochemistry; Enzyme; Immunology; Leishmaniasis; Membrane; Intracellular; Visceral leishmaniasis; World Wide Web; Computer science; Vesicle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001626247,0.0003845942,0.0003170475,0.0001560024,0.0001316721,0.0004299492,0.0002732883,0.0003543201,0.0006678737],"category_scores_gemma":[0.0001490308,0.0002141663,0.0002118959,0.0000909872,0.0003159615,0.0002268884,0.0003451622,0.0004066497,0.0002821925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002750669,"about_ca_system_score_gemma":0.0002848551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006048054,"about_ca_topic_score_gemma":0.0007626361,"domain_scores_codex":[0.9998468,0.00003292035,0.00001998168,0.00002548851,0.00003194224,0.00004281957],"domain_scores_gemma":[0.9998984,0.00002142099,0.00002725609,0.00001182395,0.00001106793,0.00002998425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007817003,0.00001231248,0.0001304457,0.00004791731,0.000005664751,0.00006212621,0.0000115837,0.00002543142,0.9990504,0.0001065697,0.00001325021,0.0004560172],"study_design_scores_gemma":[0.00002307149,0.0002367284,0.003614605,0.000008794469,0.00002249174,0.000445495,0.0000354803,0.0006863067,0.9926453,0.00006845205,0.002208646,0.000004638388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962141,0.001235587,0.001632905,0.00008884497,0.00001551186,0.00002200295,0.0001141281,0.00005021015,0.0006266353],"genre_scores_gemma":[0.9966468,0.0008014332,0.001026988,0.00005250191,0.000004255155,0.00002924204,0.0001946784,0.00001476838,0.001229247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006678737,"threshold_uncertainty_score":0.002234221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04140155384732089,"score_gpt":0.3007951864626457,"score_spread":0.2593936326153248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}