{"id":"W2024396003","doi":"10.1371/journal.ppat.1000628","title":"The Leishmania donovani Lipophosphoglycan Excludes the Vesicular Proton-ATPase from Phagosomes by Impairing the Recruitment of Synaptotagmin V","year":2009,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Fonds Québécois de la Recherche sur la Nature et les Technologies; Armand-Frappier Foundation; Colorado State University","keywords":"Lipophosphoglycan; Phagosome; Leishmania donovani; Leishmania; Cell biology; Synaptotagmin 1; Chemistry; ATPase; Biology; Biochemistry; Enzyme; Immunology; Leishmaniasis; Membrane; Intracellular; Visceral leishmaniasis; World Wide Web; Computer science; Vesicle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489842,0.0002220068,0.0002871729,0.00003674557,0.0006071926,0.00008600438,0.0005598692,0.00007051649,0.00009871366],"category_scores_gemma":[0.0003781356,0.0001011367,0.0001934225,0.0003457157,0.000308411,0.00007067203,0.0001087161,0.0003531842,0.00004809629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001127423,"about_ca_system_score_gemma":0.0001813744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001224959,"about_ca_topic_score_gemma":0.00002714494,"domain_scores_codex":[0.9979619,0.000156898,0.0004143396,0.0003290057,0.0006332589,0.0005046311],"domain_scores_gemma":[0.9977746,0.0004493286,0.0001621203,0.00126369,0.0001740405,0.0001762265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001842284,0.0005239972,0.002149527,0.00002394336,0.0002879254,0.00002109574,0.0006675828,0.000001692794,0.9627494,0.001126147,0.006527092,0.02573737],"study_design_scores_gemma":[0.001259601,0.001041343,0.2302361,0.0001570868,0.0002589957,0.0000394245,0.001523328,0.0002667387,0.6233295,0.001065895,0.1405701,0.0002518518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689796,0.005604229,0.00005825981,0.01975172,0.00005745795,0.004264344,0.0002819196,0.00007278446,0.0009296926],"genre_scores_gemma":[0.9959803,0.001373391,0.000232279,0.0005958708,0.0002226419,0.0009849141,0.00006076584,0.00002941211,0.0005204677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3394199,"threshold_uncertainty_score":0.4670096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04140155384732089,"score_gpt":0.3007951864626457,"score_spread":0.2593936326153248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}