{"id":"W2024399113","doi":"10.1593/neo.06283","title":"Three-Color FISH Analysis of TMPRSS2/ERG Fusions in Prostate Cancer Indicates That Genomic Microdeletion of Chromosome 21 Is Associated with Rearrangement","year":2006,"lang":"en","type":"article","venue":"Neoplasia","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"TMPRSS2; Fusion gene; Biology; Fluorescence in situ hybridization; Erg; Chromosomal translocation; Fusion transcript; Molecular biology; Gene rearrangement; Chimeric gene; Chromosomal rearrangement; Cancer research; Genetics; Breakpoint; Gene; Karyotype; Chromosome; Pathology; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001388753,0.0002214597,0.0001222333,0.0006089967,0.0002099868,0.0001594479,0.0001043974,0.0002840704,0.002317061],"category_scores_gemma":[0.0002393491,0.0001404856,0.0001451638,0.0002278168,0.0004332437,0.0001692495,0.0001810461,0.0001637503,0.00024879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002437097,"about_ca_system_score_gemma":0.0001191491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001349004,"about_ca_topic_score_gemma":0.002325714,"domain_scores_codex":[0.9999158,0.00001455651,0.000005113202,0.00002125276,0.00002182077,0.00002143279],"domain_scores_gemma":[0.9999121,0.00002969026,0.00001611944,0.00001138796,0.00001116759,0.00001949169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002985412,0.00002311565,0.02717492,0.00005899001,0.0000343264,0.003379976,0.0001320649,0.0003539505,0.9621718,0.0003683256,0.0001558659,0.005848243],"study_design_scores_gemma":[0.00008664982,0.0009180009,0.4943548,0.0000161214,0.0001923619,0.07567035,0.0005303492,0.004549564,0.4165699,0.001421888,0.005640748,0.00004931116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958473,0.0005071347,0.001891242,0.0000792531,0.000003742789,0.000008279582,0.00008564107,0.000052879,0.001524495],"genre_scores_gemma":[0.9989881,0.0001393775,0.0004197765,0.00001393464,0.000001707256,0.000003103674,0.00006334179,0.000004685662,0.0003659138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002317061,"threshold_uncertainty_score":0.007751346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698011405250232,"score_gpt":0.2733154797476255,"score_spread":0.2563353656951232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}