{"id":"W2024421793","doi":"10.1038/cgt.2008.95","title":"Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Pusan National University","keywords":"HBx; Hepatitis B virus; Hepatocellular carcinoma; Cancer research; Transfection; Virology; Biology; Apoptosis; Downregulation and upregulation; Interferon; Virus; Cell culture; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277198,0.0002339921,0.0002892053,0.000198126,0.0002071313,0.0003691966,0.0002227364,0.0003213566,0.001546352],"category_scores_gemma":[0.0002003121,0.000175699,0.0002070906,0.0001414541,0.0003372451,0.0002718201,0.0001579437,0.0006432005,0.0004091685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003750976,"about_ca_system_score_gemma":0.0002387037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001123234,"about_ca_topic_score_gemma":0.0008930239,"domain_scores_codex":[0.999804,0.00004699909,0.00001510002,0.0000274876,0.00004269757,0.00006382678],"domain_scores_gemma":[0.9998528,0.00007019615,0.00001862937,0.00002783362,0.00001017187,0.0000204171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001419183,0.00006280834,0.00006971398,0.00001780744,0.000004030887,0.00002800201,0.0000392275,0.000132421,0.9979823,0.0003856308,0.00005037953,0.00108582],"study_design_scores_gemma":[0.00001588607,0.0002169779,0.0003990757,0.000001496861,0.000005411693,0.00005297053,0.00001854798,0.0009259451,0.9976242,0.00002714042,0.0007107359,0.000001436535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955019,0.0006216491,0.001913301,0.0000907501,0.00002650655,0.00001829234,0.00008621176,0.00006128951,0.00168009],"genre_scores_gemma":[0.9951525,0.0002875458,0.00129368,0.00001850175,0.000006599273,0.00001328796,0.0002195429,0.00002253045,0.002985736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001546352,"threshold_uncertainty_score":0.005173087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0488495526840784,"score_gpt":0.3167823982392811,"score_spread":0.2679328455552026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}