{"id":"W2024421793","doi":"10.1038/cgt.2008.95","title":"Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Pusan National University","keywords":"HBx; Hepatitis B virus; Hepatocellular carcinoma; Cancer research; Transfection; Virology; Biology; Apoptosis; Downregulation and upregulation; Interferon; Virus; Cell culture; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002611345,0.0001739862,0.0008398048,0.0001500418,0.00004515419,0.000001226154,0.0002027847,0.0001249808,0.0004373745],"category_scores_gemma":[0.00002826303,0.0001456829,0.0002134247,0.0002007533,0.0003617841,0.00006522162,0.000042286,0.0001640879,0.000001596316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008554356,"about_ca_system_score_gemma":0.0002697769,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01211748,"about_ca_topic_score_gemma":0.0001618164,"domain_scores_codex":[0.9981448,0.0002345569,0.0006259092,0.0002916293,0.0003613505,0.0003417458],"domain_scores_gemma":[0.998688,0.0000187705,0.0003131187,0.0005291469,0.0002466765,0.0002042929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001464034,0.0004657181,0.3081683,0.00006804536,0.00004936408,0.00004194007,0.0002719002,0.00001661801,0.6834862,8.688083e-7,0.0006075184,0.005359448],"study_design_scores_gemma":[0.003924029,0.003708151,0.04868892,0.0001246426,0.00001840261,0.00001909758,0.00002138483,0.0003341121,0.9424765,0.00002092782,0.0005769484,0.00008684798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933199,0.005514414,0.0002687694,0.00009488624,0.000079159,0.0004923222,0.0001463253,0.00001348737,0.00007075063],"genre_scores_gemma":[0.9731665,0.02399819,0.002170082,0.0001392141,0.0001673562,0.00007284484,0.00003759889,0.00002855254,0.0002197152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2594794,"threshold_uncertainty_score":0.9944609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0488495526840784,"score_gpt":0.3167823982392811,"score_spread":0.2679328455552026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}