{"id":"W2024464130","doi":"10.1016/j.cellimm.2012.11.004","title":"High dose antigen treatment with a peptide epitope of myelin basic protein modulates T cells in multiple sclerosis patients","year":2012,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"GDI Integrated Facility Services (Canada); University of Alberta","funders":"Alberta Innovates","keywords":"Peripheral blood mononuclear cell; Myelin basic protein; FOXP3; Immunology; Epitope; Antigen; IL-2 receptor; Myelin; Biology; Multiple sclerosis; Stimulation; T cell; In vitro; Immune system; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002860904,0.0004439241,0.0007708815,0.000351635,0.000168378,0.000009910566,0.0003473754,0.0004494576,0.0004561158],"category_scores_gemma":[0.00003997122,0.0003503897,0.0001647392,0.0002992234,0.0005491455,0.0002199302,0.0001042508,0.0003079609,0.0004171389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001506923,"about_ca_system_score_gemma":0.00009114783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00154253,"about_ca_topic_score_gemma":0.00004024693,"domain_scores_codex":[0.9972081,0.0007325694,0.0006807118,0.0003971858,0.00005819514,0.0009232989],"domain_scores_gemma":[0.9986455,0.0001980938,0.0003371949,0.0007046866,0.0000866789,0.00002783742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003319318,0.001857023,0.03665587,0.00001877928,0.000519239,0.000004055888,0.001523548,0.00001557108,0.9431305,0.00008599969,0.0000177922,0.0128523],"study_design_scores_gemma":[0.00808708,0.001923951,0.1097549,0.0001155787,0.00003808632,0.000007461666,0.0002068981,0.000002498827,0.8726988,0.00001635483,0.006813594,0.0003348162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733337,0.02475267,0.00005415722,0.00004912692,0.000607045,0.001053658,0.00005421536,0.00005349017,0.0000419353],"genre_scores_gemma":[0.9967484,0.001197256,0.0003289762,0.00002683168,0.0000225635,0.0001735415,0.0002288276,0.0000598439,0.001213795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07309905,"threshold_uncertainty_score":0.9998948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01681708882293937,"score_gpt":0.192784669068694,"score_spread":0.1759675802457546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}