{"id":"W2024464130","doi":"10.1016/j.cellimm.2012.11.004","title":"High dose antigen treatment with a peptide epitope of myelin basic protein modulates T cells in multiple sclerosis patients","year":2012,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"GDI Integrated Facility Services (Canada); University of Alberta","funders":"Alberta Innovates","keywords":"Peripheral blood mononuclear cell; Myelin basic protein; FOXP3; Immunology; Epitope; Antigen; IL-2 receptor; Myelin; Biology; Multiple sclerosis; Stimulation; T cell; In vitro; Immune system; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897089,0.0002245469,0.0003982987,0.0002211659,0.0002481241,0.0002453472,0.0001431782,0.0004572008,0.001177393],"category_scores_gemma":[0.0004907353,0.0001230099,0.0001737352,0.0001731237,0.0002756003,0.0001882077,0.00008632586,0.0003995588,0.0002119177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001534554,"about_ca_system_score_gemma":0.0001232618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002133429,"about_ca_topic_score_gemma":0.0002076856,"domain_scores_codex":[0.9998832,0.00004504518,0.00000867266,0.00001854232,0.00001204345,0.00003248827],"domain_scores_gemma":[0.9998307,0.00005937691,0.00002839406,0.00001354164,0.0000114236,0.00005655026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.07950843,0.008872738,0.1582813,0.0003233521,0.0002352727,0.005159401,0.0008365886,0.0004205159,0.6725504,0.0003160712,0.00108413,0.07241175],"study_design_scores_gemma":[0.002805798,0.05750904,0.9017617,0.00003795426,0.0003575549,0.004749594,0.0004148696,0.000624718,0.02960614,0.0004679667,0.001638928,0.00002579355],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999508,0.000152873,0.00002374995,0.00002761155,0.000006149757,0.000004867884,0.000009225595,0.000003363933,0.0002640587],"genre_scores_gemma":[0.9996607,0.00007166217,0.0000203247,0.0000367635,0.0000176284,0.000006187881,0.00002075451,0.000001195149,0.0001647371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001177393,"threshold_uncertainty_score":0.003938794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01681708882293937,"score_gpt":0.192784669068694,"score_spread":0.1759675802457546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}