{"id":"W2024469844","doi":"10.1073/pnas.1310658110","title":"RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":481,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Wellcome Trust; GlaxoSmithKline; Pfizer","keywords":"Bromodomain; Selectivity; Chemistry; BET inhibitor; Biochemistry; Gene; Epigenetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02047971555116908,"score_gpt":0.2644422861358543,"score_spread":0.2439625705846852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}