{"id":"W2024495468","doi":"10.1002/ddr.10433","title":"Pharmacogenomics in sepsis and septic shock","year":2005,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Pharmacogenomics; Candidate gene; Single-nucleotide polymorphism; Haplotype; Sepsis; Genomics; Bioinformatics; Medicine; Biology; Allele; Genetics; Gene; Genome; Immunology; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001907201,0.0002212611,0.000654163,0.001400385,0.0001716957,0.0008211554,0.0001804606,0.0005247392,0.002519343],"category_scores_gemma":[0.00366296,0.00008211775,0.0002623166,0.002169267,0.0004342694,0.0003026273,0.0003993496,0.0005471626,0.0003012142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003073402,"about_ca_system_score_gemma":0.0005961074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004028518,"about_ca_topic_score_gemma":0.0005141424,"domain_scores_codex":[0.9987972,0.0009024196,0.00006734394,0.00006320444,0.0001403258,0.00002944419],"domain_scores_gemma":[0.9972689,0.001879766,0.0005098106,0.00006953497,0.0001658845,0.000106187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002030737,0.0003796999,0.237192,0.003659042,0.001659122,0.002724088,0.0002121737,0.004824342,0.01013258,0.02717258,0.01025006,0.6997635],"study_design_scores_gemma":[0.0004740387,0.002878393,0.6235673,0.002288083,0.00202088,0.01469125,0.00062008,0.01763508,0.01121972,0.2072573,0.117194,0.0001538069],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3583559,0.5257106,0.04310789,0.04457432,0.0009231647,0.0001427598,0.002609624,0.0001971754,0.02437854],"genre_scores_gemma":[0.8887734,0.09294374,0.01215127,0.00233004,0.001060828,0.00007546735,0.0006495286,0.00001214273,0.002003566],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002519343,"threshold_uncertainty_score":0.01008636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03731906316939672,"score_gpt":0.3379535748499911,"score_spread":0.3006345116805944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}