{"id":"W2024619620","doi":"10.1534/genetics.115.175919","title":"Interplay Between Histone H3 Lysine 56 Deacetylation and Chromatin Modifiers in Response to DNA Damage","year":2015,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; DNA damage; Histone; Acetylation; Histone H3; Chromatin; Histone H2A; Lysine; DNA; Molecular biology; DNA repair; DNA replication; DNA methylation; Biochemistry; Cell biology; Gene; Gene expression; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004749574,0.0001325948,0.0001407721,0.00009423674,0.00002282593,0.00002303129,0.0001340881,0.000140421,0.000004059465],"category_scores_gemma":[0.0001963433,0.000145531,0.00003087967,0.0001127304,0.00003816022,0.000003668143,0.0001798625,0.00006031869,0.00001512754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005851058,"about_ca_system_score_gemma":0.00007169222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001331681,"about_ca_topic_score_gemma":0.00007148993,"domain_scores_codex":[0.999035,0.000128697,0.0002074,0.0002968643,0.0001302896,0.0002017629],"domain_scores_gemma":[0.9993665,0.0000147337,0.00005087286,0.0003364261,0.00005542627,0.0001760132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002135361,0.00001872882,0.001827946,0.000006445196,0.00001562976,0.000004275368,0.0004139058,0.0002805576,0.993705,0.000008976703,0.0009738503,0.002531192],"study_design_scores_gemma":[0.001402958,0.001016063,0.02740353,0.00002613806,0.00003116792,0.000009935865,0.0003163336,0.0009171069,0.9533263,0.0002819713,0.01489906,0.0003694293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935796,0.0002543505,0.005394445,0.0002782385,0.00007892463,0.0002095414,0.0000146499,0.00001500105,0.000175308],"genre_scores_gemma":[0.9854977,0.00001144108,0.01371136,0.0001431822,0.0001054235,0.00001352369,0.00006380687,0.00002469786,0.0004288282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04037865,"threshold_uncertainty_score":0.593458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01811116953785263,"score_gpt":0.3066381020713307,"score_spread":0.2885269325334781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}