{"id":"W2024619620","doi":"10.1534/genetics.115.175919","title":"Interplay Between Histone H3 Lysine 56 Deacetylation and Chromatin Modifiers in Response to DNA Damage","year":2015,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; DNA damage; Histone; Acetylation; Histone H3; Chromatin; Histone H2A; Lysine; DNA; Molecular biology; DNA repair; DNA replication; DNA methylation; Biochemistry; Cell biology; Gene; Gene expression; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204608,0.0004132145,0.000336349,0.0002064989,0.000170756,0.0003529325,0.0002472833,0.0002981795,0.0008578904],"category_scores_gemma":[0.000109798,0.0002374251,0.0003345362,0.00016837,0.0003960689,0.0001973097,0.0003036226,0.0002671828,0.0002627591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004026654,"about_ca_system_score_gemma":0.0001960925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000906942,"about_ca_topic_score_gemma":0.001125489,"domain_scores_codex":[0.9998958,0.000009927707,0.00001140939,0.00003099884,0.00002969759,0.00002214355],"domain_scores_gemma":[0.9998469,0.000015557,0.00005936536,0.00002280711,0.00001589121,0.00003951867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005557325,0.000003922434,0.0004866704,0.00001517699,0.00000488566,0.00002535531,0.000006425627,0.0000575049,0.9989011,0.00002689239,0.000003935601,0.0004124797],"study_design_scores_gemma":[0.000008315479,0.0001379235,0.02163798,0.00000332313,0.0000179443,0.0001630328,0.0000263434,0.0006539776,0.9767044,0.00007196931,0.0005669329,0.00000802006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973901,0.001054884,0.0009709605,0.00003554561,0.000008336648,0.000007685912,0.0001407981,0.00003649795,0.0003551814],"genre_scores_gemma":[0.998175,0.0003816817,0.0006216434,0.00002571505,0.000004134168,0.000006194708,0.0001884678,0.00001379672,0.0005833034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000906942,"threshold_uncertainty_score":0.002921522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01811116953785263,"score_gpt":0.3066381020713307,"score_spread":0.2885269325334781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}