{"id":"W2024749881","doi":"10.1002/pmic.200300400","title":"Observation of multiple isoforms and specific proteolysis patterns of proliferating cell nuclear antigen in the context of cell cycle compartments and sample preparations","year":2003,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Northeast Cancer Centre","funders":"","keywords":"Proliferating cell nuclear antigen; Biology; Proteolysis; DNA replication; Cell cycle; Molecular biology; Gene isoform; Isoelectric focusing; Biochemistry; DNA polymerase delta; Cell biology; DNA; Cell; Enzyme; Gene; Reverse transcriptase; Polymerase chain reaction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003544232,0.0006845252,0.0003682086,0.0006777369,0.0003954376,0.0004026949,0.0002675578,0.00031701,0.0007948148],"category_scores_gemma":[0.0004250474,0.0002376987,0.0002580965,0.0005897909,0.0004301028,0.0002692624,0.0003719582,0.0006313361,0.000340923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720517,"about_ca_system_score_gemma":0.0002718387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006759388,"about_ca_topic_score_gemma":0.001082048,"domain_scores_codex":[0.9996443,0.00004651713,0.00002783897,0.000126402,0.00008645005,0.00006846436],"domain_scores_gemma":[0.9997005,0.0000783564,0.00005588463,0.00003957217,0.00006374895,0.00006191683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000843931,0.00001136013,0.0003155566,0.00004723539,0.00001313613,0.00007266438,0.00004558592,0.00001298581,0.998422,0.00003003478,0.0000227835,0.0009222162],"study_design_scores_gemma":[0.00001243499,0.0001427852,0.02416187,0.00001477316,0.00007183506,0.001100119,0.0001209754,0.0005567725,0.9707938,0.0001219547,0.002888153,0.00001457988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955333,0.007129498,0.03376276,0.0001866046,0.0001143277,0.0001221135,0.0007742905,0.0001898651,0.002387472],"genre_scores_gemma":[0.9444118,0.006272452,0.04025792,0.0003524963,0.0001105443,0.0004284906,0.003744175,0.0002683833,0.004153776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007948148,"threshold_uncertainty_score":0.002658963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01665658553726914,"score_gpt":0.2267621383949091,"score_spread":0.21010555285764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}