{"id":"W2024789005","doi":"10.1016/j.artres.2008.08.306","title":"07.04 LOEYS-DIETZ SYNDROME (LDS): IN VITRO STUDIES OF SKIN FIBROBLASTS SHOWING DIFFERENCES BETWEEN MUTATIONS IN THE TGFBR1 AND TGFBR2 GENES","year":2008,"lang":"en","type":"article","venue":"Artery Research","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; In vitro; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001422742,0.0001320616,0.0002639508,0.0002413464,0.0001947182,0.0000192295,0.0003691073,0.0001446201,0.00000862673],"category_scores_gemma":[0.0002401902,0.00009553961,0.00005464651,0.0003663309,0.0009451692,0.000009073363,0.0002809149,0.0003211735,0.00001029704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000168743,"about_ca_system_score_gemma":0.00009872112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007426454,"about_ca_topic_score_gemma":0.0001382434,"domain_scores_codex":[0.9976931,0.0007882942,0.000286949,0.0003824056,0.0003492442,0.0004999843],"domain_scores_gemma":[0.998988,0.0004818225,0.00003321512,0.0003197807,0.0001189062,0.00005829805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002220656,0.0001999005,0.5001788,0.0001153124,0.0001774853,0.0003688781,0.003224281,0.000008848194,0.4897278,0.00003167526,0.0002772014,0.005467846],"study_design_scores_gemma":[0.001438182,0.001608173,0.7733545,0.0001224827,0.00001252748,0.0005147397,0.008943338,0.00009567845,0.2121625,0.001000726,0.0004225838,0.000324565],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994458,0.004526125,0.00001131831,0.0004134503,0.00002062783,0.0002956386,0.0000148226,0.000003230617,0.0002568277],"genre_scores_gemma":[0.9976934,0.001731151,0.00006429297,0.00001854482,0.00006463348,0.00007735233,0.00005195193,0.00001112377,0.0002875936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2775652,"threshold_uncertainty_score":0.3895992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1213889614096195,"score_gpt":0.3700025327875937,"score_spread":0.2486135713779742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}