{"id":"W2024789005","doi":"10.1016/j.artres.2008.08.306","title":"07.04 LOEYS-DIETZ SYNDROME (LDS): IN VITRO STUDIES OF SKIN FIBROBLASTS SHOWING DIFFERENCES BETWEEN MUTATIONS IN THE TGFBR1 AND TGFBR2 GENES","year":2008,"lang":"en","type":"article","venue":"Artery Research","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; In vitro; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003589956,0.0004831354,0.0002522464,0.0006484922,0.0002878576,0.0003136852,0.0003072954,0.0005083171,0.06283415],"category_scores_gemma":[0.0004533443,0.0001500823,0.000270359,0.0001891573,0.0003778603,0.0002616993,0.0003691407,0.0007278562,0.005757033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001610444,"about_ca_system_score_gemma":0.0001864804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005624402,"about_ca_topic_score_gemma":0.0003478593,"domain_scores_codex":[0.9996386,0.0001050624,0.00002271608,0.00006306089,0.0001064664,0.00006416314],"domain_scores_gemma":[0.99965,0.00009473298,0.0000402788,0.00003262299,0.00002643413,0.0001558477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005997407,0.001524317,0.1000891,0.0003493822,0.0003548209,0.01664214,0.0004749265,0.0004151574,0.7742368,0.007390721,0.009044793,0.08348054],"study_design_scores_gemma":[0.0005903032,0.003856525,0.6451976,0.0003205722,0.0002581103,0.1296824,0.0008873027,0.002589951,0.162323,0.002760724,0.05147003,0.000063536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9627951,0.001170234,0.002553716,0.0008682124,0.0002933883,0.00005111946,0.002709881,0.0002600335,0.02929831],"genre_scores_gemma":[0.9515893,0.0006615481,0.003524819,0.0002945641,0.0001235248,0.00007971597,0.002873286,0.0001287323,0.04072442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06283415,"threshold_uncertainty_score":0.2102011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1213889614096195,"score_gpt":0.3700025327875937,"score_spread":0.2486135713779742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}