{"id":"W2024836545","doi":"10.1089/1084978041424990","title":"Engineered Fusion Hybrid Vaccine of IL-18 Gene-Modified Tumor Cells and Dendritic Cells Induces Enhanced Antitumor Immunity","year":2004,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"CTL*; Immunotherapy; Immune system; Antigen; Dendritic cell; Immunology; Cell fusion; Immunization; Biology; Interleukin 12; Cytotoxic T cell; Cell culture; In vitro; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003440403,0.000399514,0.0007083628,0.0002093201,0.0002999524,0.00003162154,0.0002556565,0.0002036821,0.0005563896],"category_scores_gemma":[0.00001629796,0.0003395001,0.0001224242,0.00021107,0.0004854065,0.0001765441,0.0000607912,0.0004370417,0.00001385287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006055749,"about_ca_system_score_gemma":0.000142813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001286804,"about_ca_topic_score_gemma":0.000001655867,"domain_scores_codex":[0.9981216,0.0002701203,0.0005659834,0.0004385679,0.00006920035,0.0005345542],"domain_scores_gemma":[0.9990957,0.0002167971,0.0001894013,0.0003320579,0.00008888305,0.00007720607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002165712,0.0002284246,0.00002312258,0.0001302203,0.0003806252,0.0000125689,0.0005263595,0.00004636095,0.9873964,0.0001353436,0.00006201628,0.008892814],"study_design_scores_gemma":[0.00779094,0.0004050791,0.001070424,0.0001744483,0.00009203098,0.0001179467,0.00009597178,0.000009931572,0.9828539,0.00006816378,0.00692323,0.0003978757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8815799,0.1160448,0.000379366,0.0002532119,0.0009274869,0.0004809435,0.0002391053,0.0000613313,0.00003387379],"genre_scores_gemma":[0.9205903,0.07828441,0.0001752957,0.0005904989,0.00006045788,0.00003942014,0.00002013533,0.00004177581,0.0001977095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03901043,"threshold_uncertainty_score":0.9999057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02081627550124255,"score_gpt":0.3005928175866874,"score_spread":0.2797765420854448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}