{"id":"W2024888186","doi":"10.1371/journal.pmed.1000028","title":"Systematic Reviews of Genetic Association Studies","year":2009,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Medical Research Council","keywords":"Systematic review; Meta-analysis; Association (psychology); Genetic association; Genome-wide association study; MEDLINE; Medicine; Biology; Genetics; Psychology; Single-nucleotide polymorphism; Genotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.07229033,0.00290036,0.01399369,0.02659076,0.001078459,0.003351913,0.003812958,0.003460316,0.006869758],"category_scores_gemma":[0.3367472,0.002634075,0.01227836,0.02484641,0.001998282,0.002643468,0.003168966,0.002255342,0.0008227893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005605617,"about_ca_system_score_gemma":0.02090334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01106548,"about_ca_topic_score_gemma":0.03205875,"domain_scores_codex":[0.8398787,0.09525001,0.04144065,0.007574794,0.01438528,0.001470601],"domain_scores_gemma":[0.6352076,0.2959659,0.03845442,0.008998601,0.01989536,0.001478132],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0006303109,0.00003280431,0.00216256,0.8761343,0.07282776,0.0001788359,0.0002988801,0.0002801032,0.0002009588,0.0006190753,0.005623179,0.04101109],"study_design_scores_gemma":[0.003043115,0.0004961927,0.01216892,0.5749797,0.3739802,0.0004266397,0.0004802568,0.0003034442,0.0003678427,0.002832026,0.03080513,0.0001164941],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002004283,0.9901206,0.001374181,0.001322279,0.0009172985,0.001384271,0.002264411,0.00004915851,0.0005634491],"genre_scores_gemma":[0.0529249,0.930678,0.007156534,0.002269004,0.0006922707,0.004160739,0.001778794,0.00004628861,0.0002934377],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9860063,"threshold_uncertainty_score":0.3823124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03535142491993398,"score_gpt":0.3108847140812902,"score_spread":0.2755332891613562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}