{"id":"W2024888186","doi":"10.1371/journal.pmed.1000028","title":"Systematic Reviews of Genetic Association Studies","year":2009,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Medical Research Council","keywords":"Systematic review; Meta-analysis; Association (psychology); Genetic association; Genome-wide association study; MEDLINE; Medicine; Biology; Genetics; Psychology; Single-nucleotide polymorphism; Genotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003172173,0.0001052271,0.0004161005,0.0000369431,0.00002734105,0.000002033063,0.000089332,0.00005962752,0.0000195028],"category_scores_gemma":[0.003394395,0.00007757635,0.00006719244,0.00006934672,0.0000393799,0.000001231586,0.00001337898,0.00002836961,0.000007846199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002103759,"about_ca_system_score_gemma":0.00001768332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001190935,"about_ca_topic_score_gemma":0.000001908933,"domain_scores_codex":[0.9989276,0.000127448,0.000473397,0.0001585533,0.0001922515,0.0001207811],"domain_scores_gemma":[0.9991349,0.00004923677,0.0002780236,0.0002577659,0.0002154036,0.0000646902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009939144,0.0006187668,0.008390089,0.02548727,0.0006463874,0.000008494267,0.0008505594,0.000008863092,0.8668305,0.00008881198,0.09594648,0.001024331],"study_design_scores_gemma":[0.02371627,0.01972215,0.1183097,0.06932785,0.01084584,0.0001006923,0.006827014,0.000325901,0.6723456,0.01556403,0.05964156,0.003273335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7187458,0.2753924,0.000294463,0.002358851,0.0003147455,0.001394141,0.0000105397,0.00001980228,0.001469228],"genre_scores_gemma":[0.9592338,0.03734836,0.0004904457,0.001281847,0.0007205745,0.00004712589,0.00004258891,0.000009974719,0.0008252471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.240488,"threshold_uncertainty_score":0.4063653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03535142491993398,"score_gpt":0.3108847140812902,"score_spread":0.2755332891613562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}