{"id":"W2024903800","doi":"10.1016/s1470-2045(13)70383-8","title":"Preference for subcutaneous or intravenous administration of trastuzumab in patients with HER2-positive early breast cancer (PrefHer): an open-label randomised study","year":2013,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":226,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Trastuzumab; Medicine; Clinical endpoint; Breast cancer; Internal medicine; Population; Surgery; Oncology; Clinical trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002659823,0.001924875,0.003997881,0.0004095032,0.0004496199,0.001322066,0.001017964,0.002410488,0.01332424],"category_scores_gemma":[0.00397851,0.001042018,0.003174162,0.0005573138,0.002101356,0.002009904,0.0007123486,0.004056325,0.001572273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001028014,"about_ca_system_score_gemma":0.0009456885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000899806,"about_ca_topic_score_gemma":0.001212163,"domain_scores_codex":[0.9979176,0.001265679,0.0001354574,0.0003184877,0.0001146063,0.0002481755],"domain_scores_gemma":[0.9967957,0.00170681,0.0005475562,0.0003033679,0.000106915,0.0005396201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.990814,0.002619814,0.0002624343,0.0002154458,0.0002863348,0.00001635655,0.00003070487,0.0001180633,0.0005112535,0.00005812192,0.0001449092,0.0049226],"study_design_scores_gemma":[0.9138457,0.08357419,0.0009955157,0.00002920196,0.0004478204,0.00001830922,0.00003034081,0.0003715608,0.0001524534,0.0001951109,0.0003165549,0.00002328463],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989872,0.002599799,0.001032756,0.0005287073,0.0007452136,0.002524179,0.0007623244,0.00006713687,0.001867988],"genre_scores_gemma":[0.9926318,0.001225527,0.001036779,0.0006735959,0.0005382432,0.001716919,0.000435056,0.00002018631,0.00172197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01332424,"threshold_uncertainty_score":0.04457402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1108922508937797,"score_gpt":0.4132427304703756,"score_spread":0.3023504795765959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}