{"id":"W2024925929","doi":"10.1111/j.1600-0854.2007.00692.x","title":"RACK1 Regulates the Cell Surface Expression of the G Protein‐Coupled Receptor for Thromboxane A<sub>2</sub>","year":2007,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Hôpital Fleurimont; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; G protein-coupled receptor; Receptor; Biology; HEK 293 cells; Protease-activated receptor 2; 5-HT5A receptor; Protease-activated receptor; Cell surface receptor; Thromboxane receptor; Endoplasmic reticulum; Prostaglandin E2 receptor; Signal transduction; Biochemistry; Thromboxane A2; Thrombin; Agonist; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071876,0.0004562935,0.0002011905,0.0002689755,0.0003166122,0.0005267562,0.0002631412,0.0002803184,0.001949208],"category_scores_gemma":[0.0000919432,0.000238019,0.0003143825,0.0001440133,0.0001997535,0.0001969252,0.000282259,0.0005953299,0.001416115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005446016,"about_ca_system_score_gemma":0.0001666458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000698987,"about_ca_topic_score_gemma":0.001079001,"domain_scores_codex":[0.9998537,0.0000224912,0.00001051966,0.0000361415,0.00002752943,0.00004957788],"domain_scores_gemma":[0.9999052,0.0000125564,0.00003775285,0.000008917769,0.00001604286,0.00001937162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001425384,0.00002329237,0.0004612546,0.00005389024,0.000008619568,0.00008149034,0.00002788557,0.00009915902,0.9966151,0.0003612305,0.0002520468,0.001873408],"study_design_scores_gemma":[0.00003390254,0.0001155593,0.02849093,0.00001908843,0.00004415346,0.0007012638,0.0001276259,0.006377671,0.9451791,0.0002476417,0.01864705,0.00001600539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793896,0.007917007,0.006367878,0.0004143199,0.0001350492,0.0000403078,0.001153255,0.0002927471,0.004289657],"genre_scores_gemma":[0.9899294,0.002266752,0.002023536,0.000131297,0.00003035831,0.00005410539,0.001276226,0.00007831074,0.004210127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001949208,"threshold_uncertainty_score":0.006520808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007645962068838153,"score_gpt":0.2163533324137616,"score_spread":0.2087073703449235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}