{"id":"W2024940370","doi":"10.1107/s1744309113005678","title":"Structure of a filament of stacked octamers of human DMC1 recombinase","year":2013,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Research Council Canada; Western Economic Diversification Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Saskatchewan; Canadian Light Source","keywords":"RAD51; Recombinase; Homologous recombination; Histone octamer; DNA; Protein filament; Homologous chromosome; Biology; Cohesin; Biophysics; Branch migration; Cell biology; Molecular biology; Holliday junction; Genetics; Recombination; Nucleosome; Gene; Chromatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005769389,0.0002345085,0.0001483293,0.0002683147,0.0003247441,0.0003281591,0.000280153,0.0003463254,0.001015073],"category_scores_gemma":[0.0001550943,0.0002164625,0.0001789988,0.0002310015,0.0002001245,0.0002304456,0.0001420548,0.0003304096,0.0002693456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005799361,"about_ca_system_score_gemma":0.0002386668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002346432,"about_ca_topic_score_gemma":0.001572996,"domain_scores_codex":[0.9999532,0.000004720059,0.000002254761,0.00001660971,0.00001242153,0.00001083746],"domain_scores_gemma":[0.9998024,0.00001924652,0.00007610114,0.00001383153,0.00002223231,0.00006610557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004355896,0.00007380794,0.002814999,0.0001419954,0.00005242608,0.001024704,0.0001659358,0.003904436,0.9842069,0.001471807,0.0007983803,0.004908999],"study_design_scores_gemma":[0.0002124669,0.0009890868,0.1811285,0.0001876189,0.00023171,0.003992836,0.0004830357,0.09176733,0.6903162,0.001559202,0.02898986,0.0001421437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947041,0.00114111,0.001674419,0.00009334171,0.00001700101,0.00001465853,0.0004173488,0.00008534946,0.001852761],"genre_scores_gemma":[0.995222,0.0003840118,0.001910842,0.00004058917,0.00000771011,0.00001055821,0.001179724,0.00001113608,0.001233368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002346432,"threshold_uncertainty_score":0.004665613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029076616793595,"score_gpt":0.2630961424429546,"score_spread":0.2528053762750186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}