{"id":"W2024960352","doi":"10.1158/1538-7445.pedcan-b45","title":"Abstract B45: A novel therapeutic approach for neuroblastoma","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Neuroblastoma; SOX2; Cancer research; Tumor progression; Metastasis; Biology; Cell culture; Cancer; Chemistry; Molecular biology; Internal medicine; Medicine; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007700976,0.0002952618,0.0002458692,0.0002619615,0.0001406697,0.0002472112,0.0002595992,0.0002790084,0.001735528],"category_scores_gemma":[0.00002987405,0.00007780037,0.0002299649,0.0001525391,0.0001309022,0.000138502,0.0001758317,0.0005169028,0.0004092234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002366941,"about_ca_system_score_gemma":0.0003213352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001604405,"about_ca_topic_score_gemma":0.003404477,"domain_scores_codex":[0.9999634,0.000006251761,0.000002960477,0.000007806128,0.000009427346,0.00001011542],"domain_scores_gemma":[0.9999892,0.000001069847,0.000002017798,0.000001085395,0.000001348735,0.000005364899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006996506,0.0003697808,0.0004238867,0.0004305393,0.00004809653,0.0003372061,0.00004945702,0.0005119368,0.9457344,0.00116456,0.001004568,0.04922574],"study_design_scores_gemma":[0.000877679,0.01029036,0.01175356,0.0001545959,0.0003128333,0.002953455,0.0001179301,0.002461208,0.8634695,0.0005720237,0.1069948,0.00004205409],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9230677,0.04744092,0.009058585,0.0008828917,0.0003880305,0.0004410427,0.001359292,0.0004135697,0.01694794],"genre_scores_gemma":[0.9704892,0.0180976,0.003722776,0.0002545613,0.00004657035,0.0001281246,0.0007439046,0.0000169731,0.006500142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001735528,"threshold_uncertainty_score":0.005805969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07683666766544858,"score_gpt":0.3962251027473787,"score_spread":0.3193884350819302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}