{"id":"W2024974995","doi":"10.1016/j.pain.2013.11.004","title":"The gap junction blocker carbenoxolone attenuates nociceptive behavior and medullary dorsal horn central sensitization induced by partial infraorbital nerve transection in rats","year":2013,"lang":"en","type":"article","venue":"Pain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"Carbenoxolone; Infraorbital nerve; Nociception; Neuropathic pain; Medicine; Anesthesia; Receptive field; Nociceptor; Stimulation; Trigeminal nerve; Gap junction; Sensitization; Neuroscience; Chemistry; Internal medicine; Psychology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005588074,0.000156491,0.0001684729,0.00005343838,0.0001509405,0.000039502,0.00002245232,0.0001362248,0.00003417555],"category_scores_gemma":[0.0001007224,0.0001149696,0.00004268055,0.0001390762,0.00004424158,0.0001207385,0.00001007496,0.0001762833,0.00001360382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001020584,"about_ca_system_score_gemma":0.00002969841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001743921,"about_ca_topic_score_gemma":0.0002762826,"domain_scores_codex":[0.9986744,0.0004131825,0.0002090315,0.0002321821,0.0001753423,0.0002958801],"domain_scores_gemma":[0.9995149,0.0001614744,0.00006045304,0.0001075603,0.00006022074,0.00009536334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003258571,0.0004982281,0.1731756,0.00003253545,0.000144689,0.00006538642,0.002544215,0.000009826355,0.7695515,0.00004926251,0.0008844893,0.05271837],"study_design_scores_gemma":[0.005268907,0.001644935,0.8774477,0.0001365837,0.0004549261,0.0000910035,0.002444484,0.01805774,0.09332188,0.0005019266,0.0001621501,0.0004678193],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968123,0.0002080319,0.0005932304,0.00128034,0.0002009783,0.0008219802,0.000006232952,0.00003512037,0.00004181522],"genre_scores_gemma":[0.9991831,0.0000422846,0.00008242134,0.0001456949,0.0001043626,0.0001663966,0.00013633,0.00001985176,0.0001196245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.704272,"threshold_uncertainty_score":0.4688324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01143320239832245,"score_gpt":0.2359657531975441,"score_spread":0.2245325507992217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}