{"id":"W2025018203","doi":"10.1111/j.1432-0436.2008.00283.x","title":"Retinoid acid-induced effects on atrial and pacemaker cell differentiation and expression of cardiac ion channels","year":2008,"lang":"en","type":"article","venue":"Differentiation","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal","funders":"Deutsche Forschungsgemeinschaft","keywords":"Biology; Embryoid body; Embryonic stem cell; Internal medicine; Endocrinology; Cellular differentiation; Retinoid; Pacemaker potential; Retinoic acid; Phenotype; Embryonic heart; Cell biology; Myocyte; Patch clamp; Atrial natriuretic peptide; Heart development; Electrophysiology; Gene; Medicine; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002305298,0.0003211247,0.00039084,0.0003375047,0.0002982981,0.0004710522,0.0002115813,0.000301511,0.002575383],"category_scores_gemma":[0.0003142372,0.0002350977,0.0003510383,0.0002571199,0.0004658152,0.0003171391,0.0002280203,0.0008918921,0.0006208216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000484489,"about_ca_system_score_gemma":0.0004836358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002505479,"about_ca_topic_score_gemma":0.003538491,"domain_scores_codex":[0.9997941,0.00005082359,0.00002698577,0.00003322626,0.00003216511,0.00006282057],"domain_scores_gemma":[0.9996909,0.0001329244,0.00003289702,0.00004972615,0.00002978555,0.00006378111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008121482,0.00002515813,0.0001478303,0.00002754745,0.00000670257,0.0001059986,0.00005432322,0.00003638063,0.997354,0.0001734753,0.00002480161,0.00123166],"study_design_scores_gemma":[0.00002104948,0.0001367331,0.001942397,0.000003439689,0.00001232026,0.00008730611,0.00004350749,0.0001245273,0.9965672,0.0000472345,0.001009768,0.000004498037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893139,0.003466367,0.002094814,0.0001608023,0.00007412869,0.00003453154,0.0005235351,0.00008380885,0.004248044],"genre_scores_gemma":[0.988436,0.001638358,0.001671691,0.0000655992,0.00001448201,0.00003797956,0.0004840981,0.00003890748,0.007612759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002575383,"threshold_uncertainty_score":0.008615434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008189179827414711,"score_gpt":0.2326615927070534,"score_spread":0.2244724128796387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}