{"id":"W2025080754","doi":"10.1002/eji.200323351","title":"Signaling through HLA‐DR induces PKCβ‐dependent B cell death outside rafts","year":2003,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"","keywords":"Cell biology; LYN; Lipid raft; Programmed cell death; Protein kinase C; Biology; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204775,0.000286914,0.0001267601,0.0001888279,0.0002143585,0.0002455534,0.0001174556,0.0001740697,0.001392512],"category_scores_gemma":[0.0001497097,0.0001572013,0.0001982897,0.00009795825,0.0001756997,0.0002696982,0.0002819857,0.0005243141,0.0009824828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000254417,"about_ca_system_score_gemma":0.0001360973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002899814,"about_ca_topic_score_gemma":0.0003312594,"domain_scores_codex":[0.9998753,0.00001960077,0.000007323231,0.00002130823,0.00002857961,0.00004792044],"domain_scores_gemma":[0.9998904,0.00002058384,0.00003126898,0.00001660913,0.00001350474,0.00002770065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001530548,0.00002369569,0.0002296627,0.00003390602,0.000004264194,0.00008834524,0.00001527231,0.00005606543,0.9978679,0.0001118286,0.00003412225,0.001381753],"study_design_scores_gemma":[0.00004717851,0.0002221619,0.00553675,0.000006816027,0.00001109226,0.0005411912,0.00004527621,0.0008604363,0.9907739,0.0002062116,0.001744812,0.000004230416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995769,0.001209701,0.0014397,0.0000813662,0.00001372009,0.00001155368,0.0001029915,0.00003842188,0.001333568],"genre_scores_gemma":[0.9972541,0.0009764121,0.0005837845,0.00003573087,0.000008893368,0.00001324595,0.0001709856,0.000006850474,0.0009500208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001392512,"threshold_uncertainty_score":0.004658401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02445703253018981,"score_gpt":0.2307813678938823,"score_spread":0.2063243353636925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}