{"id":"W2025080754","doi":"10.1002/eji.200323351","title":"Signaling through HLA‐DR induces PKCβ‐dependent B cell death outside rafts","year":2003,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"","keywords":"Cell biology; LYN; Lipid raft; Programmed cell death; Protein kinase C; Biology; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00172757,0.0005222688,0.0009183092,0.0003471407,0.0004051219,0.00004759738,0.001079671,0.0003415277,0.001639874],"category_scores_gemma":[0.000286155,0.0004360218,0.0003971474,0.0002219114,0.000495947,0.0003182609,0.0002242455,0.001876436,0.002621564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009842939,"about_ca_system_score_gemma":0.000223487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000246923,"about_ca_topic_score_gemma":0.000002159365,"domain_scores_codex":[0.9931763,0.003737268,0.001518244,0.0004779448,0.0001074004,0.0009828707],"domain_scores_gemma":[0.9973938,0.0003486277,0.001269639,0.0005969222,0.0003347828,0.00005623875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003267388,0.000447452,0.0004259495,0.00001276093,0.0007249387,0.0007122449,0.001341665,0.00003936633,0.9915616,0.001239115,0.001768735,0.00139946],"study_design_scores_gemma":[0.004983177,0.001690774,0.0008733798,0.00007457267,0.0001754647,0.004628778,0.001647829,1.884993e-7,0.8454332,0.0005214576,0.1394977,0.0004734366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9279045,0.02968906,0.00126246,0.0003598209,0.004732963,0.0001677826,0.000008472914,0.00007473238,0.03580024],"genre_scores_gemma":[0.9907494,0.001292128,0.0009976297,0.0004587386,0.0001366194,0.000002463325,0.00001492136,0.00008890437,0.006259217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1461283,"threshold_uncertainty_score":0.9998091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02445703253018981,"score_gpt":0.2307813678938823,"score_spread":0.2063243353636925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}