{"id":"W2025151319","doi":"10.1016/j.neulet.2011.03.091","title":"Cystatin C induces apoptosis and tyrosine hydroxylase gene expression through JNK-dependent pathway in neuronal cells","year":2011,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital","funders":"","keywords":"Molecular biology; Apoptosis; Biology; Cellular differentiation; Signal transduction; Protein kinase A; Kinase; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002539031,0.0003342594,0.0004683904,0.0004248137,0.0004278241,0.0003511263,0.0002854967,0.0003943081,0.0009626403],"category_scores_gemma":[0.0001994714,0.0001751168,0.0005472396,0.0003666803,0.0003842602,0.0003311495,0.0002663318,0.000978475,0.000225746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006735653,"about_ca_system_score_gemma":0.0007312598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002293923,"about_ca_topic_score_gemma":0.002995112,"domain_scores_codex":[0.9997473,0.0000361622,0.00003318715,0.00003030942,0.00005397276,0.00009908475],"domain_scores_gemma":[0.9998335,0.0000277406,0.00002837019,0.00003604143,0.00003845118,0.00003583552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001059223,0.0001395437,0.0004764433,0.00008954073,0.00003138416,0.0002587233,0.0000552205,0.000063648,0.9958631,0.0001295835,0.0001085335,0.001725142],"study_design_scores_gemma":[0.00007753297,0.0003569798,0.007864529,0.000006339989,0.00004071716,0.0003722115,0.00009414113,0.0005638089,0.9894618,0.00008659613,0.001068545,0.00000690447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955707,0.001811659,0.0009144729,0.0001261894,0.00005203158,0.00002787088,0.0001740613,0.00003116922,0.001291882],"genre_scores_gemma":[0.9955146,0.000947993,0.0007413427,0.00005876442,0.00001653737,0.00004580582,0.0004194147,0.000006961203,0.002248623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002293923,"threshold_uncertainty_score":0.004887044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03603179045074221,"score_gpt":0.2567182046529972,"score_spread":0.220686414202255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}