{"id":"W2025182563","doi":"10.1021/jm200750x","title":"Proteolytically Stable Cancer Targeting Peptides with High Affinity for Breast Cancer Cells","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Breast cancer; Cancer; Cancer cell; Cancer research; Biochemistry; Combinatorial chemistry; Computational biology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002959182,0.000164223,0.0003068972,0.00001464971,0.00005773113,0.0000115062,0.0002245743,0.0001230541,0.0006194052],"category_scores_gemma":[0.00008492854,0.0001103679,0.0001553715,0.00006863767,0.0001062983,0.000005369688,0.00003448265,0.000181683,4.025437e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004162981,"about_ca_system_score_gemma":0.0002454536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001105986,"about_ca_topic_score_gemma":0.0000115131,"domain_scores_codex":[0.9989135,0.00001292936,0.0003616615,0.000197135,0.0002596047,0.0002551698],"domain_scores_gemma":[0.9988541,0.00002366285,0.0003801144,0.0001286733,0.0004114584,0.0002019724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007183962,0.000107476,0.002273038,0.0001508823,0.0002412176,0.000009643674,0.00003261595,0.00002605717,0.9932117,9.955528e-7,0.002036628,0.001191341],"study_design_scores_gemma":[0.0007072869,0.0001295443,0.0007543269,0.0002039526,0.000246399,0.00005501071,0.0001620823,0.00001429447,0.9959033,0.00002798061,0.00163804,0.0001578438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977123,0.0009076028,0.0004368428,0.0004031376,0.00005087917,0.00007543827,0.00007238251,0.000003466718,0.0003380184],"genre_scores_gemma":[0.9950209,0.0003230958,0.002881554,0.0001228462,0.001195112,0.00002215038,0.000005735766,0.00002138624,0.0004071762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00269153,"threshold_uncertainty_score":0.6782053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088388616047957,"score_gpt":0.2326531733554068,"score_spread":0.2217692871949273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}