{"id":"W2025182563","doi":"10.1021/jm200750x","title":"Proteolytically Stable Cancer Targeting Peptides with High Affinity for Breast Cancer Cells","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Breast cancer; Cancer; Cancer cell; Cancer research; Biochemistry; Combinatorial chemistry; Computational biology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002566343,0.0003029006,0.000287735,0.0001293676,0.00009632435,0.0002509584,0.0002055943,0.0002700787,0.0007233215],"category_scores_gemma":[0.0002665269,0.0001631218,0.0002129127,0.0001547353,0.000180295,0.0001923995,0.0001437965,0.000507437,0.0004194939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001832046,"about_ca_system_score_gemma":0.0001368325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001553726,"about_ca_topic_score_gemma":0.0002509481,"domain_scores_codex":[0.9998429,0.00004109569,0.00001803487,0.00002855959,0.00003813892,0.0000312542],"domain_scores_gemma":[0.999767,0.00004351543,0.00008979603,0.00002262901,0.00003479448,0.00004236453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007120673,0.00001177993,0.00006139078,0.00003043322,0.00000264261,0.00004430769,0.000009577488,0.00008137929,0.9981658,0.00003262427,0.00001743822,0.001471491],"study_design_scores_gemma":[0.00003525666,0.0006700947,0.001048695,0.000005310279,0.00001402493,0.0007117971,0.00001028636,0.0002792583,0.9928741,0.00001979723,0.004324178,0.000007187445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851241,0.003096222,0.009064372,0.0001126462,0.00004355049,0.000140083,0.0002122094,0.00006809764,0.002138687],"genre_scores_gemma":[0.9713489,0.002728419,0.02236629,0.00019901,0.00003676925,0.0001011963,0.0005787576,0.00003931646,0.00260134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007233215,"threshold_uncertainty_score":0.00241977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088388616047957,"score_gpt":0.2326531733554068,"score_spread":0.2217692871949273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}