{"id":"W2025218334","doi":"10.1002/biot.201500056","title":"Modulating secretory pathway pH by proton channel co‐expression can increase recombinant protein stability in plants","year":2015,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicago (Canada); Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Recombinant DNA; Proteolysis; Biochemistry; Heterologous expression; Biology; Cell biology; Hemagglutinin (influenza); Nicotiana benthamiana; Chemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005223714,0.0001630917,0.0001747989,0.00008073592,0.0001219704,0.00001824492,0.0002846479,0.000491743,0.000008333916],"category_scores_gemma":[0.00009490842,0.0001395392,0.00004377482,0.00007863114,0.0001097307,0.000006725846,0.00007119562,0.0004683962,0.000003151873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006244461,"about_ca_system_score_gemma":0.0002195334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007434934,"about_ca_topic_score_gemma":0.00007207911,"domain_scores_codex":[0.9987785,0.0001077601,0.0003231849,0.0003272247,0.0001301107,0.0003331766],"domain_scores_gemma":[0.9993199,0.000005403627,0.0001659454,0.0003001075,0.00004338486,0.0001653236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001187623,0.0001632098,0.001784679,0.00001013418,0.00001005559,0.00001210662,0.00005563496,0.00000733443,0.9952894,0.00001681305,0.0007922896,0.001739508],"study_design_scores_gemma":[0.001126396,0.0002501911,0.0004502386,0.0000542936,0.000002487927,0.0001680796,0.0002209756,0.0001016313,0.9853044,0.0005802187,0.01155605,0.0001850063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968176,0.0003949704,0.001085983,0.0007395567,0.0000677164,0.0006249248,0.0001447158,0.00003062141,0.00009384986],"genre_scores_gemma":[0.9990036,0.0001354577,0.0004273299,0.00004666656,0.00006154355,0.0001306392,0.0001291935,0.00001691045,0.00004859062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01076376,"threshold_uncertainty_score":0.5690244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02082913321913825,"score_gpt":0.2441157672082686,"score_spread":0.2232866339891303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}