{"id":"W2025291890","doi":"10.1210/jc.2011-0685","title":"More than Inflammation: Interleukin-1β Polymorphisms and the Lipid Metabolism","year":2011,"lang":"en","type":"letter","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Radboud Universitair Medisch Centrum; Radboud Universiteit","keywords":"Apolipoprotein E; Inflammation; LDL receptor; Endocrinology; Receptor; Foam cell; Internal medicine; Apolipoprotein B; Lipid metabolism; Knockout mouse; Receptor antagonist; Biology; Lipoprotein; Cytokine; Interleukin; Immunology; Medicine; Cholesterol; Antagonist; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001032641,0.0006625408,0.001872007,0.0005760399,0.00131821,0.002008019,0.0006637941,0.00817567,0.008496717],"category_scores_gemma":[0.006001212,0.0003920651,0.0005577634,0.0008035934,0.001021154,0.002453602,0.000512149,0.01176755,0.003730902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009739854,"about_ca_system_score_gemma":0.0006272335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001113641,"about_ca_topic_score_gemma":0.001762272,"domain_scores_codex":[0.9991504,0.0002809247,0.0001183568,0.0001049545,0.0002648804,0.00008038893],"domain_scores_gemma":[0.9976488,0.00158135,0.0001524241,0.00008191389,0.0003406975,0.0001947916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0003784608,0.00008885936,0.003992708,0.0002969998,0.00006108642,0.01023566,0.000265172,0.00007320387,0.001214675,0.002789532,0.9406595,0.03994404],"study_design_scores_gemma":[0.0005671278,0.0003234786,0.01818477,0.001671052,0.0002317733,0.04800781,0.001005715,0.0008045283,0.001653708,0.01960802,0.9078106,0.0001314092],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003501869,0.02601952,0.0002437206,0.91866,0.04507759,0.00001093018,0.0001294463,0.00004218859,0.006314809],"genre_scores_gemma":[0.05013295,0.03711422,0.000649606,0.5227243,0.3498544,0.00004233513,0.0001755614,0.00006032054,0.03924633],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.008496717,"threshold_uncertainty_score":0.02842438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03632191781576371,"score_gpt":0.2905497385656005,"score_spread":0.2542278207498367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}