{"id":"W2025295789","doi":"10.1210/en.2010-0022","title":"Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion","year":2010,"lang":"en","type":"review","venue":"Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":761,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neurokinin B; Kisspeptin; Arcuate nucleus; Dynorphin; Endocrinology; Internal medicine; Gonadotropin-releasing hormone; Hypothalamus; Biology; Neuropeptide; Hormone; Luteinizing hormone; Medicine; Receptor; Substance P; Opioid peptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003787798,0.001208049,0.001319225,0.001512526,0.0002814643,0.0008920748,0.001090583,0.0009428136,0.0100256],"category_scores_gemma":[0.0004881819,0.0002625235,0.0003195474,0.001852618,0.0004577562,0.001688718,0.0005110097,0.00165979,0.008816033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005156919,"about_ca_system_score_gemma":0.0008946322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006216982,"about_ca_topic_score_gemma":0.0008703339,"domain_scores_codex":[0.9998265,0.00002257693,0.00002580187,0.00002953649,0.00007957836,0.00001600373],"domain_scores_gemma":[0.9997075,0.00006258974,0.00004438735,0.000008568938,0.0001126905,0.00006424038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000109993,0.00006081865,0.0002931817,0.01317576,0.0001162,0.0004751346,0.00006959433,0.000266417,0.005475475,0.001402735,0.2495058,0.729049],"study_design_scores_gemma":[0.00001182167,0.00003259438,0.001277226,0.00087682,0.00005465553,0.002042581,0.00004294427,0.00004160294,0.0004218766,0.0006048907,0.9945814,0.00001157441],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003213942,0.9890219,0.0002808265,0.0009756529,0.005217427,0.00001535919,0.00005941829,0.00003324359,0.004074859],"genre_scores_gemma":[0.001357007,0.9877192,0.0003377042,0.0005494214,0.005121314,0.00001357933,0.0001353556,0.00000763653,0.004758831],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0100256,"threshold_uncertainty_score":0.03353894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02777863020820122,"score_gpt":0.292027240910752,"score_spread":0.2642486107025508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}