{"id":"W2025350140","doi":"10.1021/bi900831k","title":"Regulation of Process Retraction and Cell Migration by EphA3 Is Mediated by the Adaptor Protein Nck1","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Core Research for Evolutional Science and Technology; National Institute of Environmental Health Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Eye Institute","keywords":"Erythropoietin-producing hepatocellular (Eph) receptor; Cell biology; SH2 domain; Signal transducing adaptor protein; Ephrin; Biology; Mutant; Receptor; Cell migration; Receptor tyrosine kinase; Angiogenesis; Protein kinase domain; Signal transduction; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007113805,0.00008272531,0.00006523912,0.000008885625,0.00008154546,0.00001784793,0.0000880638,0.00008898292,0.00001856096],"category_scores_gemma":[0.0001209014,0.00006529292,0.00001816709,0.000131544,0.00005074684,0.00009928007,0.000006152958,0.0001015554,0.000001762809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001327322,"about_ca_system_score_gemma":0.00002240641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000457758,"about_ca_topic_score_gemma":1.772091e-7,"domain_scores_codex":[0.9992665,0.00002243773,0.000157506,0.0002265971,0.0002308548,0.00009607192],"domain_scores_gemma":[0.9996183,0.00003945943,0.0001642825,0.0001118827,0.00003321297,0.00003287189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003552921,0.00003879134,0.00003882108,0.00002566981,4.450202e-7,1.90523e-7,0.00004877788,7.484636e-7,0.9933072,0.000001497106,0.00620783,0.0002945441],"study_design_scores_gemma":[0.0001395305,0.00004697459,0.0001950343,0.00002218454,0.000004216017,0.000002668384,0.00003210577,0.0005331304,0.9983328,0.00006028284,0.0005612845,0.00006980495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981372,0.0002144103,0.00004415573,0.001063781,0.00001339408,0.0001573307,0.00003333456,0.00002297554,0.0003134544],"genre_scores_gemma":[0.9988362,0.0000319577,0.00001168526,0.0003374233,0.00003840882,0.000008710645,0.00001653173,0.000005438028,0.0007136912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005646545,"threshold_uncertainty_score":0.2662568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225822332666746,"score_gpt":0.2372285064190109,"score_spread":0.2249702830923434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}