{"id":"W2025389666","doi":"10.1371/journal.ppat.0030042","title":"Transcriptional Regulation by Protein Kinase A in Cryptococcus neoformans","year":2007,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"Response Biomedical (Canada); Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canada's Michael Smith Genome Sciences Centre","keywords":"Biology; Protein kinase A; Cryptococcus neoformans; Biochemistry; Fungal protein; Gene; Cell biology; Mutant; Kinase; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007514488,0.0003346408,0.0001968929,0.000368246,0.0002173443,0.0002947162,0.0001154264,0.0002250367,0.0004568181],"category_scores_gemma":[0.0001534999,0.000123674,0.0002336187,0.0002305562,0.0002203942,0.00009179839,0.0001946234,0.0004021798,0.0003363579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008827098,"about_ca_system_score_gemma":0.0003705667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004658333,"about_ca_topic_score_gemma":0.003210878,"domain_scores_codex":[0.9998628,0.00001371537,0.00001148537,0.00004240902,0.00003533249,0.00003439002],"domain_scores_gemma":[0.9998823,0.00002035798,0.00003766004,0.00001156234,0.00002076075,0.00002730795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001065785,0.00002001645,0.0003423946,0.00002125285,0.000001566828,0.00004674787,0.000009034003,0.00009175275,0.9984871,0.00004388483,0.00004130315,0.0007884882],"study_design_scores_gemma":[0.00004203823,0.0002575348,0.05044398,0.00001672057,0.00002128891,0.0006788357,0.0001311682,0.00484938,0.9399561,0.0002506145,0.003331691,0.00002062176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955117,0.001303996,0.000797293,0.0002321392,0.00003737379,0.00001954,0.001210416,0.00007644296,0.000811074],"genre_scores_gemma":[0.9946871,0.0005000247,0.001515642,0.0001446953,0.00001057456,0.00002652674,0.00146803,0.00001872247,0.001628672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004658333,"threshold_uncertainty_score":0.009262443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180385317654973,"score_gpt":0.2533728518883374,"score_spread":0.2353343201228401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}