{"id":"W2025477540","doi":"10.1182/blood-2006-10-053256","title":"TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Universidad Pública de Navarra; Institut National Du Cancer; Universidad de Navarra","keywords":"Cytotoxic T cell; Priming (agriculture); CD8; T cell; Biology; Cell biology; TLR7; Immunology; Toll-like receptor; Immune system; Innate immune system; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001565747,0.0003295072,0.0002078322,0.0001234025,0.00006490587,0.0002679101,0.000129085,0.0002585553,0.001372243],"category_scores_gemma":[0.0002202583,0.0001340973,0.0001698036,0.00006807272,0.0001408785,0.0001663503,0.0001879398,0.0004754202,0.0006663101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001460624,"about_ca_system_score_gemma":0.0001334084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001428606,"about_ca_topic_score_gemma":0.0002402032,"domain_scores_codex":[0.999811,0.00005173261,0.00001285441,0.00002100019,0.00002953604,0.00007387605],"domain_scores_gemma":[0.9998048,0.00006167364,0.00003246383,0.00003065782,0.00002027054,0.00005016863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003514392,0.0000598331,0.0002705825,0.00003977503,0.000003932985,0.00007485723,0.00001338996,0.0001050812,0.9970592,0.00006348478,0.00006576553,0.001892736],"study_design_scores_gemma":[0.0001523595,0.001642816,0.004649562,0.00001492364,0.00002266402,0.0006661311,0.00004417947,0.001465857,0.9884863,0.0001862293,0.002662458,0.000006594097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968927,0.0007709242,0.0008757587,0.00005077126,0.00001850386,0.00001832163,0.0001294971,0.00006681048,0.001176633],"genre_scores_gemma":[0.9973496,0.0002377754,0.000941536,0.00006058312,0.00001376676,0.00002258458,0.0002846418,0.000015027,0.001074403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001372243,"threshold_uncertainty_score":0.004590631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00864944446287636,"score_gpt":0.2081221805864858,"score_spread":0.1994727361236095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}