{"id":"W2025493069","doi":"10.1242/jcs.024927","title":"Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis","year":2008,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Biology; Biogenesis; Cell biology; Membrane; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007021991,0.000318187,0.0001322575,0.0001785656,0.0001392598,0.0002968045,0.0002151547,0.0002300595,0.0006684029],"category_scores_gemma":[0.00006958764,0.0001671074,0.0001681373,0.0001302074,0.0002192954,0.0001852538,0.0001911293,0.0004142073,0.0002591708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005139504,"about_ca_system_score_gemma":0.0002174179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102965,"about_ca_topic_score_gemma":0.001375875,"domain_scores_codex":[0.9999313,0.000006131229,0.000006281022,0.00001864179,0.00002145967,0.00001610027],"domain_scores_gemma":[0.9999518,0.000007659816,0.00001440855,0.000005515928,0.000003540548,0.00001699174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008492896,0.00000766903,0.0002026624,0.00001206569,0.000002419223,0.00003451082,0.000004642922,0.00004591661,0.9990317,0.0000841886,0.0000161755,0.0004732095],"study_design_scores_gemma":[0.00001420955,0.00009215378,0.009677705,0.000003664364,0.00001418199,0.0002058639,0.00002033847,0.001671334,0.9866239,0.00008372209,0.001589105,0.000003713453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950795,0.001141301,0.0020907,0.00007265549,0.00001192332,0.00001195608,0.0004954709,0.00006178111,0.001034649],"genre_scores_gemma":[0.9950642,0.0007643728,0.001229838,0.00004400117,0.000004407969,0.00002025907,0.0007232155,0.0000170577,0.002132717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00102965,"threshold_uncertainty_score":0.003729045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007648570664655107,"score_gpt":0.2335211965216331,"score_spread":0.225872625856978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}