{"id":"W2025513151","doi":"10.1097/00004647-200111000-00007","title":"Effects of Moderate Hypothermia on IL-1β–Induced Leukocyte Rolling and Adhesion in Pial Microcirculation of Mice and on Proinflammatory Gene Expression in Human Cerebral Endothelial Cells","year":2001,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Thermal Regulation in Medicine","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; Children's Hospital of Eastern Ontario","funders":"","keywords":"Hypothermia; Intravital microscopy; Proinflammatory cytokine; Neuroprotection; Microcirculation; Pharmacology; Intercellular Adhesion Molecule-1; Cell adhesion molecule; Inflammation; Adhesion; Medicine; Chemistry; Immunology; Anesthesia; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007193491,0.0002804887,0.0009877264,0.0006953486,0.00004209333,0.00001251888,0.000101383,0.0002116195,0.00001458052],"category_scores_gemma":[0.0001462914,0.0002230252,0.0001223525,0.0002025947,0.00007797184,0.0002261285,0.0000317352,0.000511584,5.774794e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005439268,"about_ca_system_score_gemma":0.00009992684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002461447,"about_ca_topic_score_gemma":0.000006229375,"domain_scores_codex":[0.9974428,0.0002859887,0.001140645,0.0002462781,0.0006168589,0.0002674546],"domain_scores_gemma":[0.9984829,0.0002002291,0.0008280287,0.0001752774,0.0001451828,0.0001684113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003705753,0.0004341878,0.006047324,0.0002684942,0.00005895471,0.00008997957,0.001379461,0.001233276,0.9834518,0.00003612182,0.000003726846,0.003290894],"study_design_scores_gemma":[0.01603576,0.0007644472,0.1636351,0.001508213,0.0001995848,0.000129721,0.00005904819,0.0009938262,0.8163396,0.0001854217,0.00001570907,0.0001335843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980275,0.0009398971,0.00005205435,0.000090609,0.0002487689,0.0005906671,0.000004166955,0.00001094382,0.00003536494],"genre_scores_gemma":[0.9973074,0.0002048781,0.00173788,0.00008170502,0.0005779506,0.00000502048,0.000002417973,0.00005418705,0.00002856678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1671123,"threshold_uncertainty_score":0.9094703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092506968230039,"score_gpt":0.2423948304665102,"score_spread":0.2314697607842098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}