{"id":"W2025544481","doi":"10.1016/j.physbeh.2013.07.014","title":"Hypothalamic malonyl-CoA and the control of food intake","year":2013,"lang":"en","type":"review","venue":"Physiology & Behavior","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Malonyl-CoA; Endocrinology; Anorectic; Internal medicine; Carnitine O-palmitoyltransferase; Leptin; Biology; Arcuate nucleus; Hypothalamus; Cerulenin; Chemistry; Beta oxidation; Fatty acid synthase; Lipid metabolism; Metabolism; Food intake; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004720683,0.0009988506,0.001210744,0.001289557,0.0002508508,0.001122259,0.0009840103,0.00105593,0.00286915],"category_scores_gemma":[0.0003965122,0.0002533882,0.0002701897,0.002334977,0.0008856884,0.001039942,0.0008354516,0.001503087,0.001872052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008663228,"about_ca_system_score_gemma":0.001270374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00241704,"about_ca_topic_score_gemma":0.004309617,"domain_scores_codex":[0.999903,0.00001241977,0.00001217472,0.00002077292,0.00003819326,0.00001358195],"domain_scores_gemma":[0.9998349,0.00004285227,0.00003457004,0.000005805163,0.00004962614,0.00003229974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001720723,0.00007197365,0.0002965125,0.007340395,0.000106252,0.0002764199,0.00004499955,0.000556612,0.004595993,0.003979282,0.02404268,0.9585169],"study_design_scores_gemma":[0.00004019556,0.00009175776,0.002962333,0.002011357,0.0001431046,0.001268372,0.0001021501,0.0002077401,0.001126831,0.005159008,0.9868509,0.0000362389],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001665256,0.9983568,0.0001992124,0.0002345211,0.0001567209,0.000003008876,0.00002029093,0.000006516643,0.0008565063],"genre_scores_gemma":[0.0009432564,0.9980363,0.0001576075,0.00007796774,0.0002058966,0.000003934925,0.0000282509,0.000001064155,0.0005457432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00286915,"threshold_uncertainty_score":0.009598315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05587690522841378,"score_gpt":0.3034574335344453,"score_spread":0.2475805283060315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}