{"id":"W2025661917","doi":"10.1038/emboj.2008.210","title":"Human DNA polymerase iota protects cells against oxidative stress","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"Institute of Cancer Research; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Biology; Oxidative stress; Polymerase; DNA polymerase; DNA; Molecular biology; Polymerase chain reaction; DNA damage; Oxidative phosphorylation; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417741,0.0005586258,0.0004844374,0.0003037537,0.0002367129,0.000652693,0.0002840344,0.0004110908,0.001827551],"category_scores_gemma":[0.0003581226,0.0003485321,0.0003495819,0.0002024738,0.0002978011,0.0002674484,0.000426808,0.0006956613,0.0007635699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002336893,"about_ca_system_score_gemma":0.0002698952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000378337,"about_ca_topic_score_gemma":0.0003354401,"domain_scores_codex":[0.9998212,0.00002500986,0.00001697223,0.00005663105,0.00002973083,0.00005049471],"domain_scores_gemma":[0.9995951,0.00007562499,0.00009029114,0.0001213514,0.00003554132,0.00008204146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007419464,0.00004715453,0.0006069324,0.00004339784,0.00002074719,0.00003634986,0.00001568915,0.00004549964,0.9963964,0.00008123621,0.00007066005,0.001894032],"study_design_scores_gemma":[0.00005358262,0.0004157794,0.00384317,0.000010222,0.00002301726,0.0001352655,0.00002787667,0.0002803927,0.993286,0.0001237455,0.001795188,0.000005783751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987017,0.004849662,0.005458958,0.0002629781,0.0002053417,0.00003788718,0.0006955722,0.0002655791,0.00120708],"genre_scores_gemma":[0.9931669,0.00124035,0.001385359,0.00006777965,0.00004541726,0.00002167955,0.001800687,0.00005060095,0.002221287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001827551,"threshold_uncertainty_score":0.006113708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305389049509561,"score_gpt":0.2400810069854303,"score_spread":0.2270271164903346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}