{"id":"W2025661917","doi":"10.1038/emboj.2008.210","title":"Human DNA polymerase iota protects cells against oxidative stress","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"Institute of Cancer Research; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Biology; Oxidative stress; Polymerase; DNA polymerase; DNA; Molecular biology; Polymerase chain reaction; DNA damage; Oxidative phosphorylation; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002522332,0.0001621021,0.000125684,0.0000343653,0.0005136395,0.00003590828,0.0003931255,0.00008097335,0.0000647237],"category_scores_gemma":[0.00003113941,0.0001130005,0.0001241469,0.00006171106,0.0001099678,0.000003794771,0.0001224636,0.000282697,0.00002726915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001868262,"about_ca_system_score_gemma":0.00008948602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000613144,"about_ca_topic_score_gemma":0.000006036662,"domain_scores_codex":[0.9989162,0.0001797607,0.000203027,0.0001939826,0.000213735,0.0002932985],"domain_scores_gemma":[0.9992617,0.000006812674,0.0001642888,0.0003591367,0.00007908692,0.0001289437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002534832,0.00006529745,0.00003141937,0.000003430377,0.00006347759,0.00008137753,0.0002042956,0.00004226086,0.9971243,0.00003392529,0.001891585,0.0004333183],"study_design_scores_gemma":[0.0004441842,0.0002137736,0.0001699523,0.00002023258,0.00001140378,0.000391129,0.0001366069,0.00001643295,0.9965528,0.0001413729,0.00174838,0.0001537293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968627,0.0002974476,0.0003202334,0.0001629531,0.0002013417,0.0001919538,0.00001247948,0.00001099327,0.001939913],"genre_scores_gemma":[0.9962574,0.00009767084,0.0003029473,0.0003938661,0.0006429021,0.0000100877,0.000008430591,0.00002849632,0.002258171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006052571,"threshold_uncertainty_score":0.4608027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305389049509561,"score_gpt":0.2400810069854303,"score_spread":0.2270271164903346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}