{"id":"W2025681917","doi":"10.1016/j.enzmictec.2008.01.019","title":"Periplasmic chaperone FkpA reduces extracytoplasmic stress response and improves cell-surface display on Escherichia coli","year":2008,"lang":"en","type":"article","venue":"Enzyme and Microbial Technology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Department of Education of Guangdong Province; Science Foundation Ireland","keywords":"Periplasmic space; Cell envelope; Escherichia coli; Chaperone (clinical); Cell; Cell biology; Biology; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108527,0.0003947425,0.0003801619,0.0001733764,0.0001567835,0.0005448916,0.000332959,0.0002997266,0.001092066],"category_scores_gemma":[0.0002104179,0.0001497975,0.0001910927,0.0002093229,0.0001470071,0.0002156124,0.0003760986,0.0006149377,0.0005574535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003018599,"about_ca_system_score_gemma":0.0001746615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009725,"about_ca_topic_score_gemma":0.001296461,"domain_scores_codex":[0.9998071,0.00002891844,0.0000142115,0.00002354759,0.00006068995,0.000065699],"domain_scores_gemma":[0.9998943,0.00001967662,0.00001949852,0.00002051116,0.00002219101,0.00002383592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005827438,0.00002081185,0.00007806106,0.000007175514,0.000001887543,0.00001389957,0.000006669989,0.00003187383,0.9989603,0.00003144225,0.00003068844,0.0007590101],"study_design_scores_gemma":[0.000002699999,0.00004320541,0.0007823151,0.000001400351,0.000004424399,0.00003392571,0.000009150604,0.0003406075,0.9984627,0.00000752307,0.0003100483,0.000002087779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972152,0.0001857511,0.001891606,0.00007217614,0.00001273659,0.000005004835,0.00008693327,0.00007736983,0.0004531978],"genre_scores_gemma":[0.9963421,0.0001479602,0.001024861,0.00004790861,0.000005059856,0.000006908541,0.0002153369,0.00004995294,0.002159762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001092066,"threshold_uncertainty_score":0.003653347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005641744482863898,"score_gpt":0.2044156941033098,"score_spread":0.1987739496204459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}