{"id":"W2025681917","doi":"10.1016/j.enzmictec.2008.01.019","title":"Periplasmic chaperone FkpA reduces extracytoplasmic stress response and improves cell-surface display on Escherichia coli","year":2008,"lang":"en","type":"article","venue":"Enzyme and Microbial Technology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Department of Education of Guangdong Province; Science Foundation Ireland","keywords":"Periplasmic space; Cell envelope; Escherichia coli; Chaperone (clinical); Cell; Cell biology; Biology; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001115425,0.0003161735,0.0002949832,0.0001270811,0.0002617126,0.00002564673,0.0002535466,0.0008427714,0.00001075715],"category_scores_gemma":[0.00005043815,0.0002976992,0.00004685513,0.0001551004,0.000795029,0.00000586912,0.0003232423,0.0003041354,0.00001100145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001388127,"about_ca_system_score_gemma":0.00007810399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001378503,"about_ca_topic_score_gemma":0.00001926176,"domain_scores_codex":[0.9984948,0.0000594824,0.0002530474,0.0006958482,0.00006016793,0.0004366796],"domain_scores_gemma":[0.9993498,0.00001953,0.0001118942,0.0003917302,0.00004193398,0.00008505512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008171479,0.0001099642,0.0001794952,0.00001413795,0.00002839165,0.00002111029,0.00006250689,0.000003216082,0.9968548,0.00008149476,0.00074858,0.0010792],"study_design_scores_gemma":[0.0009698527,0.001493206,0.001319025,0.00001637365,0.00001634369,0.0002119952,0.0001218919,0.00001173405,0.959106,0.00002389933,0.03637354,0.0003361593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957792,0.002192511,0.00002490846,0.001294891,0.0002333132,0.0002598124,0.00007204925,0.00007489722,0.00006848841],"genre_scores_gemma":[0.9939246,0.003211774,0.001218878,0.0002114243,0.00009755928,0.00001488041,0.00003437143,0.0000387675,0.001247806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03774877,"threshold_uncertainty_score":0.9999475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005641744482863898,"score_gpt":0.2044156941033098,"score_spread":0.1987739496204459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}