{"id":"W2025707029","doi":"10.1016/s0012-1606(03)00305-1","title":"Pygopus is required for embryonic brain patterning in Xenopus","year":2003,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Morpholino; Biology; Neural plate; Forebrain; Gastrulation; Neurula; Cell biology; Xenopus; Wnt signaling pathway; Neural development; Hindbrain; Neural tube; Molecular biology; Zebrafish; Embryo; Embryogenesis; Endocrinology; Signal transduction; Central nervous system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003784572,0.000224799,0.0002156263,0.00009131886,0.00009564426,0.00001655661,0.0002064671,0.0002587099,0.0001362354],"category_scores_gemma":[0.0001344628,0.0002240278,0.00007159115,0.0001345447,0.0000828289,0.000005074904,0.00007533922,0.0000858091,0.0000378663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008370259,"about_ca_system_score_gemma":0.0002538573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001044741,"about_ca_topic_score_gemma":0.00003807831,"domain_scores_codex":[0.9985077,0.00007786229,0.0003176317,0.0005352744,0.00006605861,0.0004954073],"domain_scores_gemma":[0.9996244,0.00003408318,0.00008767503,0.0001426701,0.0000465747,0.0000646431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009900489,0.00003952366,0.06028023,0.00001847667,0.00007028779,0.000003650826,0.0002290381,0.00000275824,0.9206237,0.0002861561,0.01458736,0.00375981],"study_design_scores_gemma":[0.001388091,0.0001492922,0.002515934,0.00001962233,0.000004591192,0.00002806795,0.0001431738,0.000003695126,0.6456752,0.000456588,0.3492365,0.0003792321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994097,0.0007913338,0.00170014,0.000470461,0.0005370064,0.0003462892,0.00002741471,0.00001996776,0.002010411],"genre_scores_gemma":[0.9852699,0.00007979749,0.00794524,0.002778783,0.0000836483,0.0001936761,0.0004272037,0.00003466567,0.003187102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3346491,"threshold_uncertainty_score":0.9135588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180797576004964,"score_gpt":0.2712197648903819,"score_spread":0.2531400072898854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}