{"id":"W2025753970","doi":"10.1177/0960327108090751","title":"N,N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine (DPPE; tesmilifene), a chemopotentiating agent with hormetic effects on DNA synthesis in vitro, may improve survival in patients with metastatic breast cancer","year":2008,"lang":"en","type":"article","venue":"Human & Experimental Toxicology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"In vitro; Metastatic breast cancer; Breast cancer; Cancer; Medicine; Internal medicine; Chemistry; DNA; Cancer research; Oncology; Pharmacology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001818238,0.0005743334,0.001110832,0.0004048939,0.000170653,0.00001179792,0.0001576838,0.0001483313,0.0007555165],"category_scores_gemma":[0.00002187828,0.0004492034,0.0001127423,0.0004110501,0.0003339568,0.0001081377,0.00008388823,0.000368541,0.00002442422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001325925,"about_ca_system_score_gemma":0.0001731224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048966,"about_ca_topic_score_gemma":0.0007406003,"domain_scores_codex":[0.9970361,0.0003353429,0.0005170279,0.0008231244,0.0004493297,0.0008390471],"domain_scores_gemma":[0.9988476,0.0002737528,0.0002420703,0.0003333097,0.000061835,0.0002414417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01312134,0.009542837,0.2361134,0.0002234279,0.0007428907,0.00107591,0.002261327,0.00004331372,0.7310133,0.00001671669,0.00005942274,0.005786085],"study_design_scores_gemma":[0.02019187,0.007370248,0.4307362,0.000208827,0.0002942101,0.00004771466,0.0004156212,0.00004977693,0.5401903,0.000004189723,0.00002878637,0.0004622035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964121,0.0004266865,0.000002810885,0.0002937405,0.0003144209,0.001867305,0.00003139583,0.00005740596,0.0005941209],"genre_scores_gemma":[0.9967307,0.00003246399,0.0003619662,0.0007708548,0.0001527486,0.00151075,0.00007450122,0.00009747029,0.0002685154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1946228,"threshold_uncertainty_score":0.999796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02075088809721976,"score_gpt":0.3016769680528315,"score_spread":0.2809260799556117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}