{"id":"W2025794310","doi":"10.2174/1872208311206030184","title":"Lessons Learned from Muscle Fatigue: Implications for Treatment of Patients with Hyperkalemic Periodic Paralysis","year":2012,"lang":"en","type":"review","venue":"Recent Patents on Biotechnology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Channelopathy; Periodic paralysis; Muscle weakness; Medicine; Depolarization; Hypokalemic periodic paralysis; Paralysis; Hyperkalemia; Skeletal muscle; Hypokalemia; Weakness; Muscle stiffness; Myotonia; Muscle fatigue; Internal medicine; Anesthesia; Physical medicine and rehabilitation; Electromyography; Surgery; Stiffness; Materials science; Myotonic dystrophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004654876,0.0003851462,0.0008212971,0.0002167699,0.0001039466,0.000009509491,0.0002093936,0.0009843523,0.00004061103],"category_scores_gemma":[0.00003141354,0.0002791333,0.0003146567,0.0002402433,0.0001131992,0.000003675998,0.00004362289,0.00007880059,0.00001633236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176697,"about_ca_system_score_gemma":0.00008460265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001048628,"about_ca_topic_score_gemma":0.000008489561,"domain_scores_codex":[0.9984638,0.0000704995,0.0004398585,0.0006181411,0.00009921872,0.0003084655],"domain_scores_gemma":[0.9985312,0.00002677762,0.0004968792,0.0007289104,0.0001434912,0.00007279532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007699119,0.000565083,0.0002834909,0.0001652382,0.0003467147,5.989774e-8,0.000006985097,0.000005612912,0.0003474767,0.00006999724,0.00007418315,0.9980581],"study_design_scores_gemma":[0.0009602006,0.0009590953,0.000785962,0.0001819497,0.000693121,7.401744e-7,0.000009113352,0.00000345869,0.001110694,0.00002290148,0.994992,0.000280748],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01220574,0.9782628,0.002393054,0.00103156,0.0005684298,0.002433929,0.00298713,0.00007685553,0.00004054128],"genre_scores_gemma":[0.006735628,0.9782459,0.0002937435,0.00002033025,0.000132905,0.000490047,0.01387089,0.00005918671,0.0001513802],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9977774,"threshold_uncertainty_score":0.9999661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1548346206692408,"score_gpt":0.3430570084905782,"score_spread":0.1882223878213374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}