{"id":"W2025887296","doi":"10.1155/2015/520871","title":"A Lipid Mediator Hepoxilin A3 Is a Natural Inducer of Neutrophil Extracellular Traps in Human Neutrophils","year":2015,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Neutrophil extracellular traps; Inducer; Mediator; Extracellular; Lipid signaling; Chemistry; Neutrophile; Biochemistry; Immunology; Inflammation; Biology; Cell biology; Enzyme; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000721589,0.0003203158,0.0006843512,0.0004432699,0.00005730583,0.00000909039,0.0003719649,0.000405879,0.0001989141],"category_scores_gemma":[0.0002062918,0.0002895234,0.0001585515,0.0004595395,0.0002593953,0.0003375162,0.00009391604,0.0004891498,0.00007413819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009443869,"about_ca_system_score_gemma":0.000148311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001017554,"about_ca_topic_score_gemma":0.00005953429,"domain_scores_codex":[0.9975353,0.0003506771,0.001119435,0.0003876863,0.0001992805,0.0004075563],"domain_scores_gemma":[0.9984326,0.0001059258,0.0006356656,0.0004312066,0.000315941,0.00007859554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002071432,0.0001400911,0.002334363,0.00006655627,0.00007329974,0.00001294765,0.003125075,0.00001331211,0.9886116,0.002038298,0.0002870385,0.003090215],"study_design_scores_gemma":[0.003152893,0.000379628,0.003628037,0.00008264984,0.00004537859,0.00001050351,0.0005539449,0.00001528679,0.9891583,0.00097897,0.001730825,0.0002636073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956447,0.002179389,0.00003456163,0.0004485865,0.001019418,0.0004899225,0.00003474999,0.00004351401,0.0001051453],"genre_scores_gemma":[0.9991575,0.00006361569,0.0001232408,0.00005002047,0.0002142087,0.00004789282,0.0001809307,0.0000335513,0.0001290206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003512806,"threshold_uncertainty_score":0.9999557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01758219471808194,"score_gpt":0.2475254738915888,"score_spread":0.2299432791735069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}