{"id":"W2025970242","doi":"10.1016/s0962-8924(99)01681-5","title":"No longer an exclusive club: eukaryotic signalling domains in bacteria","year":2000,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Ontario Institute for Cancer Research","funders":"Natural Sciences and Engineering Research Council of Canada; European Commission","keywords":"Biology; Phosphorylation; Cell biology; Signal transducing adaptor protein; Kinase; Signalling; Function (biology); Threonine; Phosphatase; Serine; Protein tyrosine phosphatase; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006151238,0.0006462387,0.001599731,0.0006987109,0.0005401627,0.001726762,0.001286009,0.001939862,0.00175589],"category_scores_gemma":[0.0006560076,0.000290343,0.0002156063,0.001489562,0.001388176,0.003372318,0.001117324,0.001744423,0.001651601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004722434,"about_ca_system_score_gemma":0.0007446638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004576945,"about_ca_topic_score_gemma":0.0009566602,"domain_scores_codex":[0.9998298,0.00002250416,0.00001676226,0.00003272484,0.00007083446,0.00002740988],"domain_scores_gemma":[0.9996779,0.0001520459,0.0000403397,0.0000147625,0.00005569767,0.0000592876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002883856,0.0000432029,0.0002262065,0.00565396,0.00004197937,0.0004800195,0.0001317217,0.0003981993,0.01465114,0.01367277,0.02911261,0.9352999],"study_design_scores_gemma":[0.00003515849,0.00007822803,0.0007159338,0.001078431,0.00005668336,0.001770837,0.0001406397,0.0001618681,0.003052035,0.008630693,0.9842567,0.00002265913],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001293867,0.9933755,0.001157493,0.001025853,0.0008043329,0.000004579276,0.00002805746,0.00002379807,0.002286432],"genre_scores_gemma":[0.009190833,0.9838149,0.001079012,0.001425901,0.000714163,0.00001818327,0.00007975392,0.000009822438,0.003667463],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001939862,"threshold_uncertainty_score":0.005874038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02648645697820186,"score_gpt":0.3074949201796274,"score_spread":0.2810084632014255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}