{"id":"W2025997431","doi":"10.1139/y05-006","title":"Role of the actin cytoskeleton in angiotensin II signaling in human vascular smooth muscle cells","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Hypertension Canada","keywords":"Angiotensin II; Cell biology; Actin cytoskeleton; Cytoskeleton; NADPH oxidase; Cytochalasin D; Phosphorylation; Vascular smooth muscle; Signal transduction; Cytochalasin B; Cytochalasin; Kinase; Actin; Biology; Protein kinase C; Reactive oxygen species; Chemistry; Biochemistry; Endocrinology; Cell; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002888091,0.00009357278,0.0001921714,0.0001453723,0.00008982218,0.000002497912,0.0001463991,0.0001503129,0.0001371052],"category_scores_gemma":[0.00001378552,0.00007994953,0.00008577125,0.0001048551,0.0001536589,0.000006798398,0.00003118425,0.0002134103,3.208836e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002912261,"about_ca_system_score_gemma":0.0002613346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004664054,"about_ca_topic_score_gemma":0.003242968,"domain_scores_codex":[0.9991243,0.0002046904,0.0002869554,0.0001279817,0.00003935111,0.0002166623],"domain_scores_gemma":[0.9995639,0.0000137382,0.0001710852,0.0000835636,0.00005556557,0.000112143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002679438,0.00002601042,0.0005733238,0.00000931782,0.00002093231,0.000004691663,0.000177106,0.004717147,0.9931567,0.00003045657,0.0001351014,0.001122425],"study_design_scores_gemma":[0.0008379277,0.0001274355,0.01921692,0.00002148781,0.0000167311,0.000005889506,0.00004529197,0.0001057674,0.9648817,0.0002627939,0.01439562,0.00008239202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975876,0.00181612,0.000006271884,0.0003472193,0.00009858135,0.00009796717,0.000004582625,6.234477e-7,0.00004105431],"genre_scores_gemma":[0.9991463,0.00004671156,0.00009502762,0.0004553115,0.0002303855,0.000001962603,0.000003445056,0.000007726888,0.00001308191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02827495,"threshold_uncertainty_score":0.3260247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006556832887488128,"score_gpt":0.234290206604273,"score_spread":0.2277333737167849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}