{"id":"W2026027490","doi":"10.1002/eji.201040983","title":"An intrinsic B‐cell defect supports autoimmunity in New Zealand black chromosome 13 congenic mice","year":2010,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Arthritis Research Centre of Canada; University of Toronto","funders":"Canadian Institutes of Health Research; Arthritis Society","keywords":"Biology; Congenic; Autoimmunity; B cell; Immunology; B-cell receptor; Autoantibody; Antigen; Antibody; Transgene; B-1 cell; T cell; Immune system; Molecular biology; Cell biology; Genetics; Antigen-presenting cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000458181,0.001076265,0.0005277628,0.00159721,0.0003705727,0.0006396357,0.0005453367,0.0009561076,0.003376848],"category_scores_gemma":[0.0003122858,0.0003930984,0.0003984668,0.000376137,0.0007114863,0.0003423977,0.0005558385,0.001405121,0.0009188745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003221713,"about_ca_system_score_gemma":0.0002748692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008168229,"about_ca_topic_score_gemma":0.001387788,"domain_scores_codex":[0.999359,0.0001170769,0.00007810436,0.0001510746,0.0002099236,0.00008482063],"domain_scores_gemma":[0.9987452,0.0001233763,0.0006256221,0.00009489624,0.00006035125,0.000350466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001966353,0.00006420373,0.0003318843,0.00002878926,0.00000951,0.0001717396,0.00002239946,0.00003158331,0.9983886,0.000173201,0.00002622672,0.0005551847],"study_design_scores_gemma":[0.0002829046,0.00128596,0.02698241,0.00007355562,0.0001337209,0.004168747,0.00008921119,0.001550226,0.9603606,0.00024365,0.00479521,0.00003381815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921706,0.0007235079,0.003470881,0.0001195075,0.00003252375,0.00005505664,0.0005702774,0.000197699,0.002659907],"genre_scores_gemma":[0.9851325,0.001069378,0.006285413,0.00008197434,0.00003186921,0.0001126981,0.001079901,0.0001775365,0.006028819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003376848,"threshold_uncertainty_score":0.01129669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00796751288858915,"score_gpt":0.2123361308225634,"score_spread":0.2043686179339743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}