{"id":"W2026099577","doi":"10.1152/ajpcell.00287.2008","title":"Hypothermia increases the gain of excitation-contraction coupling in guinea pig ventricular myocytes","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Heart and Stroke Foundation of Canada","keywords":"Chemistry; Hypothermia; Myocyte; Internal medicine; Contraction (grammar); Calcium; Endoplasmic reticulum; Biophysics; Voltage clamp; Electrophysiology; Caffeine; Coupling (piping); Endocrinology; Materials science; Biology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001325006,0.0003377409,0.000443957,0.00008755617,0.00009183139,0.000281173,0.0001453054,0.0001790109,0.001117102],"category_scores_gemma":[0.0002677773,0.0001916883,0.000277935,0.00005270186,0.0003492036,0.0002786294,0.0002853416,0.000482303,0.0001450923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003469753,"about_ca_system_score_gemma":0.0001627308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007564152,"about_ca_topic_score_gemma":0.0008625695,"domain_scores_codex":[0.9998753,0.0000215724,0.00001566236,0.00003209259,0.00002650871,0.00002895853],"domain_scores_gemma":[0.9998454,0.00002613167,0.00005590259,0.00002690333,0.00001747354,0.00002814564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003484761,0.00001156729,0.0005506985,0.00002520938,0.00001227753,0.00003690029,0.00001525439,0.00003594457,0.9982901,0.00002643598,0.00001709784,0.0006300605],"study_design_scores_gemma":[0.00009728081,0.002166415,0.1061402,0.00002007285,0.0001397167,0.0004167404,0.0000617834,0.001208418,0.888761,0.00009754232,0.0008767573,0.00001397486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980499,0.0007166398,0.0006715689,0.00004367555,0.00001589836,0.0000128792,0.000112458,0.00003753585,0.0003394288],"genre_scores_gemma":[0.9986461,0.0003647941,0.0004502608,0.0000425861,0.00001300144,0.0000229815,0.0001299508,0.00001632382,0.0003140798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001117102,"threshold_uncertainty_score":0.003737092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00852263302785825,"score_gpt":0.2389465374486536,"score_spread":0.2304239044207954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}