{"id":"W2026150229","doi":"10.1089/104454901300069004","title":"Alternative Promoter Usage and Splicing of <i>ZNF74</i> Multifinger Gene Produce Protein Isoforms with a Different Repressor Activity and Nuclear Partitioning","year":2001,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Calgary; Université de Montréal","funders":"Medical Research Council; Alberta Heritage Foundation for Medical Research","keywords":"Biology; Gene isoform; Alternative splicing; Molecular biology; RNA splicing; Krüppel; Rapid amplification of cDNA ends; RNA polymerase II; Repressor; RNA; Zinc finger; Complementary DNA; Gene; Gene expression; RNA-binding protein; Genetics; Promoter; Transcription factor; Molecular cloning","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009449604,0.0002577153,0.0001408482,0.00021982,0.000137393,0.000205909,0.0001696322,0.0001467149,0.0006993199],"category_scores_gemma":[0.0001557192,0.000117514,0.0003102778,0.000113941,0.0002027939,0.0001213942,0.0001584488,0.0002887487,0.0003148501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000294562,"about_ca_system_score_gemma":0.0001519314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006656109,"about_ca_topic_score_gemma":0.001156658,"domain_scores_codex":[0.9998821,0.000008781227,0.00001053914,0.00003664973,0.00003133526,0.00003064636],"domain_scores_gemma":[0.999806,0.00004219015,0.00007576894,0.00002499688,0.00002026979,0.00003077133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003501261,0.000004259852,0.0009565888,0.000008395785,0.000002878215,0.0001260741,0.00002035179,0.0000219417,0.9976888,0.0001170562,0.000009930263,0.001008803],"study_design_scores_gemma":[0.000009781175,0.0001089224,0.01968015,0.000004509699,0.00002262773,0.001633642,0.00004792781,0.0006104621,0.9749518,0.0001316218,0.002787873,0.00001066573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943531,0.0002872446,0.004618494,0.00003670932,0.00001195198,0.00000880555,0.0001983655,0.00004192656,0.0004434642],"genre_scores_gemma":[0.9918023,0.0002602923,0.005384829,0.0000307158,0.00001303665,0.00001402863,0.001118204,0.00003488173,0.001341861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006993199,"threshold_uncertainty_score":0.002339423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009694087835351181,"score_gpt":0.2348595192406041,"score_spread":0.2251654314052529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}