{"id":"W2026195537","doi":"10.1002/prp2.4","title":"Green fluorescent protein fused to peptide agonists of two dissimilar G protein‐coupled receptors: novel ligands of the bradykinin B<sub>2</sub> (rhodopsin family) receptor and parathyroid hormone <scp>PTH</scp><sub>1</sub> (secretin family) receptor","year":2013,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université Laval","funders":"","keywords":"Internalization; G protein-coupled receptor; Receptor; Green fluorescent protein; Fusion protein; Parathyroid hormone; Agonist; HEK 293 cells; Parathyroid hormone receptor; Biology; Transfection; Cell biology; Biochemistry; Chemistry; Recombinant DNA; Hormone receptor; Calcium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002887834,0.0003315184,0.0003737117,0.0001419245,0.0001437566,0.0003947173,0.0003639962,0.000594953,0.000573113],"category_scores_gemma":[0.0001399129,0.0001568441,0.0002794575,0.000173543,0.0002393758,0.0003108324,0.0003233899,0.000539044,0.0003012317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005448338,"about_ca_system_score_gemma":0.0001740846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002765974,"about_ca_topic_score_gemma":0.0003293818,"domain_scores_codex":[0.9998035,0.00003967302,0.0000125515,0.00005519806,0.0000470712,0.0000420143],"domain_scores_gemma":[0.9999189,0.00001440366,0.00001976529,0.000007347651,0.00001005897,0.00002954587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004577785,0.00001255162,0.00006077729,0.00001614239,0.000002887351,0.00003610963,0.000008572733,0.00007292127,0.9991208,0.0001235759,0.0000130523,0.0004869499],"study_design_scores_gemma":[0.00002963722,0.0002674939,0.001673733,0.000005734555,0.00002136655,0.0006134458,0.00002547628,0.002131797,0.9915359,0.00006412425,0.003619508,0.00001174312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874133,0.001274721,0.009954503,0.0001362135,0.00002113211,0.0000411597,0.0001209649,0.00005782071,0.0009800938],"genre_scores_gemma":[0.9765812,0.0008805413,0.01978381,0.000140155,0.00001293364,0.00006731822,0.0004301635,0.00002694454,0.002076971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000594953,"threshold_uncertainty_score":0.00395304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02483807847311671,"score_gpt":0.3022254399397686,"score_spread":0.2773873614666519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}