{"id":"W2026195537","doi":"10.1002/prp2.4","title":"Green fluorescent protein fused to peptide agonists of two dissimilar G protein‐coupled receptors: novel ligands of the bradykinin B<sub>2</sub> (rhodopsin family) receptor and parathyroid hormone <scp>PTH</scp><sub>1</sub> (secretin family) receptor","year":2013,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université Laval","funders":"","keywords":"Internalization; G protein-coupled receptor; Receptor; Green fluorescent protein; Fusion protein; Parathyroid hormone; Agonist; HEK 293 cells; Parathyroid hormone receptor; Biology; Transfection; Cell biology; Biochemistry; Chemistry; Recombinant DNA; Hormone receptor; Calcium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002232651,0.0007234082,0.0009219254,0.0004276276,0.0005421241,0.0001101235,0.001149665,0.0005057389,0.00006151753],"category_scores_gemma":[0.0009889798,0.0006062496,0.0003659303,0.001008654,0.001309535,0.00006398495,0.00106133,0.001090929,0.00004697767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002043546,"about_ca_system_score_gemma":0.0005768381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002660266,"about_ca_topic_score_gemma":0.00003393529,"domain_scores_codex":[0.9937618,0.001110038,0.0009923255,0.001574512,0.001092835,0.001468438],"domain_scores_gemma":[0.9962222,0.0002633206,0.0005072338,0.0008066061,0.001545495,0.0006551597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005783817,0.0007459687,0.0001533378,0.0001093961,0.0004134091,0.000003007452,0.00233611,0.00003036667,0.9825621,0.0001376502,0.01187547,0.001054756],"study_design_scores_gemma":[0.002908777,0.00204129,0.001932313,0.0001570297,0.00005794648,0.000005719738,0.004080104,0.0002272368,0.9863073,0.0001686304,0.001727429,0.0003861969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885151,0.004033392,0.0004316924,0.001160723,0.0002308861,0.005303935,0.0001470561,0.00004973073,0.0001275003],"genre_scores_gemma":[0.9936574,0.001726493,0.001583692,0.0001693514,0.0006916504,0.00164977,0.00007265355,0.0001526939,0.0002963018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01014804,"threshold_uncertainty_score":0.9996389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02483807847311671,"score_gpt":0.3022254399397686,"score_spread":0.2773873614666519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}