{"id":"W2026199073","doi":"10.1371/journal.pgen.0010063","title":"Drosophila tan Encodes a Novel Hydrolase Required in Pigmentation and Vision","year":2005,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Mental Health; Deutsche Forschungsgemeinschaft; State University of New York","keywords":"Biology; Drosophila melanogaster; Mutant; Hydrolase; Melanogaster; Ectopic expression; Drosophila virilis; Drosophilidae; Histamine; Genetics; Gene; Cell biology; Biochemistry; Molecular biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008580725,0.00009390113,0.0001073264,0.0001009734,0.00009388755,0.00001815041,0.0001342714,0.0000778636,0.00002250727],"category_scores_gemma":[0.0001349088,0.00008821596,0.00001569588,0.0001539433,0.0002129886,0.0001098887,0.00009303789,0.0001645237,0.00004433297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001910428,"about_ca_system_score_gemma":0.00002054582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000101468,"about_ca_topic_score_gemma":0.000009898882,"domain_scores_codex":[0.9990423,0.000119017,0.0001641542,0.0003356772,0.0001074955,0.0002313108],"domain_scores_gemma":[0.9995672,0.0001646652,0.00003815495,0.0001604885,0.00001356167,0.00005592576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005510143,0.0002109963,0.001199138,0.000007778362,0.00000124419,0.00000512362,0.0001638388,0.0001481535,0.9974982,0.0001608967,0.00002335378,0.0005262377],"study_design_scores_gemma":[0.0005926244,0.000311728,0.004151116,0.0000119598,0.000003260431,0.00001445421,0.00000785441,0.02055885,0.9734504,0.0006699217,0.0001369065,0.00009089789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985487,0.00007438783,0.00001017019,0.0006007904,0.0000381777,0.0001897069,0.000009394184,0.00002346002,0.0005052558],"genre_scores_gemma":[0.9985441,0.000255179,0.0002227562,0.0008102658,0.00006249703,0.00001640002,0.000003184374,0.00001073621,0.00007489102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02404771,"threshold_uncertainty_score":0.3597342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05141409010859957,"score_gpt":0.3336909920160721,"score_spread":0.2822769019074726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}