{"id":"W2026199073","doi":"10.1371/journal.pgen.0010063","title":"Drosophila tan Encodes a Novel Hydrolase Required in Pigmentation and Vision","year":2005,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Mental Health; Deutsche Forschungsgemeinschaft; State University of New York","keywords":"Biology; Drosophila melanogaster; Mutant; Hydrolase; Melanogaster; Ectopic expression; Drosophila virilis; Drosophilidae; Histamine; Genetics; Gene; Cell biology; Biochemistry; Molecular biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005555744,0.0007368975,0.0001829928,0.0003022899,0.0001309589,0.0002156686,0.0002181449,0.0002190261,0.001027364],"category_scores_gemma":[0.00009008458,0.000146848,0.0002362086,0.0001906184,0.0001759255,0.0001820938,0.0002495045,0.0002399583,0.0005849578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003338267,"about_ca_system_score_gemma":0.000216477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007547926,"about_ca_topic_score_gemma":0.001076819,"domain_scores_codex":[0.9999371,0.000006180213,0.000005776154,0.00002175524,0.00002101586,0.000008358893],"domain_scores_gemma":[0.9999175,0.00001120929,0.00002888905,0.000007909632,0.00001078357,0.00002381426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005420198,0.000006622116,0.0007085457,0.00003290782,0.000004426548,0.0002754337,0.00001094179,0.00003863532,0.9955231,0.0001139326,0.00006045388,0.00317088],"study_design_scores_gemma":[0.00002844618,0.0002130449,0.03648288,0.0000127382,0.0000447497,0.003174312,0.00006267654,0.001669358,0.9395236,0.0001708949,0.01859851,0.00001876507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732559,0.002565893,0.01761201,0.000104641,0.0001015338,0.000087311,0.002253361,0.0008235256,0.003195958],"genre_scores_gemma":[0.9716732,0.001335586,0.01477327,0.00008316615,0.00001783658,0.00004963653,0.004038298,0.0001019449,0.007927082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001027364,"threshold_uncertainty_score":0.003436923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05141409010859957,"score_gpt":0.3336909920160721,"score_spread":0.2822769019074726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}