{"id":"W2026202044","doi":"10.1016/j.neuroimage.2009.08.033","title":"Basal opioid receptor binding is associated with differences in sensory perception in healthy human subjects: A [18F]diprenorphine PET study","year":2009,"lang":"en","type":"article","venue":"NeuroImage","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Stiftung Rheinland-Pfalz für Innovation; Deutsche Forschungsgemeinschaft","keywords":"Orbitofrontal cortex; Opioid; Psychology; Neuroscience; Endogenous opioid; Opioid receptor; Premotor cortex; Nociception; Somatosensory system; Diprenorphine; Statistical parametric mapping; Threshold of pain; Medicine; Anesthesia; Internal medicine; Receptor; Anatomy; Prefrontal cortex; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002762714,0.0003873323,0.0005262229,0.0004641602,0.0005242422,0.000587534,0.0002216657,0.0006938778,0.003384378],"category_scores_gemma":[0.000531961,0.000462889,0.0002412174,0.0003058775,0.0007036572,0.0003483735,0.000221643,0.0004504443,0.0005231064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001963447,"about_ca_system_score_gemma":0.0001304493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003429498,"about_ca_topic_score_gemma":0.003115857,"domain_scores_codex":[0.9998817,0.00002248066,0.000008510607,0.00004521094,0.00001425948,0.00002781556],"domain_scores_gemma":[0.999739,0.00008363716,0.00004814591,0.00003407784,0.00002224112,0.00007289913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05019229,0.004998061,0.5830265,0.0003069008,0.0008923614,0.007631702,0.002681172,0.0003640004,0.3257749,0.0005707396,0.0006331683,0.02292827],"study_design_scores_gemma":[0.0001446942,0.001714205,0.9929367,0.000003251639,0.00009683177,0.002118811,0.000289707,0.0001851776,0.002192843,0.0001079788,0.0001992295,0.00001058335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993963,0.0001518043,0.0001025132,0.00001155931,0.000004174452,0.000011056,0.00006721579,0.000002840719,0.0002524026],"genre_scores_gemma":[0.9990532,0.0001002922,0.00008388194,0.00003800725,0.00001039423,0.00001037663,0.0001335465,0.000005675441,0.0005646687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003429498,"threshold_uncertainty_score":0.0113219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03927511069958121,"score_gpt":0.3040627713655699,"score_spread":0.2647876606659886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}