{"id":"W2026321829","doi":"10.1016/j.jviromet.2010.12.024","title":"Early detection of influenza A(H5) viruses with affinity for the human sialic acid receptor by MALDI-TOF mass spectrometry based mutation detection","year":2010,"lang":"en","type":"article","venue":"Journal of Virological Methods","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; BC Centre for Disease Control; Public Health Agency of Canada; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences","keywords":"Biology; Influenza A virus subtype H5N1; Virology; Sialic acid; Viral quasispecies; Hemagglutinin (influenza); Virus; Glycoprotein; Neuraminidase; Influenza A virus; Microbiology; Molecular biology; Genetics; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003406952,0.0005394061,0.0002756938,0.0003617702,0.0002341258,0.0003563416,0.000368443,0.0007283568,0.0009510706],"category_scores_gemma":[0.0005797379,0.0002192151,0.0002604274,0.0001518474,0.0002541494,0.0003654904,0.0002677727,0.0006605352,0.0005984349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002950505,"about_ca_system_score_gemma":0.0001864299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007570765,"about_ca_topic_score_gemma":0.0009405526,"domain_scores_codex":[0.9997354,0.00003914504,0.0000132008,0.00005807118,0.0001137863,0.00004036908],"domain_scores_gemma":[0.9997763,0.00007740288,0.0000392621,0.00001284833,0.00005834619,0.00003586188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004959439,0.00001362484,0.0004704419,0.00001311763,0.000004597252,0.00002582781,0.0000181021,0.00002973897,0.9977059,0.00005849122,0.00004472087,0.001565791],"study_design_scores_gemma":[0.000006812768,0.0001224972,0.005654275,0.000004133304,0.00001213646,0.0005235251,0.00003324693,0.003167677,0.9896808,0.00008077585,0.0007033878,0.00001059742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9530484,0.001198628,0.04208464,0.0003262987,0.00009700129,0.00008454787,0.0005582491,0.000290725,0.002311546],"genre_scores_gemma":[0.959306,0.000571659,0.03701148,0.0002424345,0.00001615352,0.00006203072,0.0004423755,0.00002968749,0.002318145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009510706,"threshold_uncertainty_score":0.003181696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111347225529861,"score_gpt":0.4509629641757172,"score_spread":0.3398282416227312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}