{"id":"W2026321829","doi":"10.1016/j.jviromet.2010.12.024","title":"Early detection of influenza A(H5) viruses with affinity for the human sialic acid receptor by MALDI-TOF mass spectrometry based mutation detection","year":2010,"lang":"en","type":"article","venue":"Journal of Virological Methods","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; BC Centre for Disease Control; Public Health Agency of Canada; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences","keywords":"Biology; Influenza A virus subtype H5N1; Virology; Sialic acid; Viral quasispecies; Hemagglutinin (influenza); Virus; Glycoprotein; Neuraminidase; Influenza A virus; Microbiology; Molecular biology; Genetics; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004352458,0.0002229841,0.0006136993,0.0003203829,0.000312306,0.00003869541,0.0002199191,0.0002736553,0.0001354442],"category_scores_gemma":[0.005963983,0.0001209144,0.0002803154,0.0004902221,0.0004287797,0.0001887589,0.00003354978,0.001282083,0.000002619981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001054345,"about_ca_system_score_gemma":0.00007503443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002953279,"about_ca_topic_score_gemma":0.00001638816,"domain_scores_codex":[0.9973505,0.0007000905,0.0007604772,0.0002211662,0.0006283243,0.0003394263],"domain_scores_gemma":[0.995948,0.002044851,0.0008517579,0.0002653217,0.0007330745,0.0001570275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00482295,0.0001903505,0.00286727,0.00005404248,0.000241634,0.000005826826,0.00007445837,0.0000302284,0.9739284,0.00001890638,0.00002388102,0.01774203],"study_design_scores_gemma":[0.002776183,0.009152759,0.0913204,0.00002926388,0.000263645,0.00004591786,0.00009489352,0.0001788548,0.892844,0.0004514296,0.0027248,0.0001178556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.724042,0.0002716332,0.2747481,0.0002212874,0.0001918551,0.0004546474,0.00001053135,0.00002101435,0.00003894817],"genre_scores_gemma":[0.8259147,0.00002206749,0.1731374,0.000505061,0.0003424536,0.00004598876,6.870462e-7,0.00002237111,0.000009256535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1018727,"threshold_uncertainty_score":0.7139875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111347225529861,"score_gpt":0.4509629641757172,"score_spread":0.3398282416227312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}