{"id":"W2026356631","doi":"10.1093/neuonc/nou237.33","title":"AT-33A PHASE II STUDY OF CONCURRENT RADIATION THERAPY, TEMOZOLOMIDE AND THE HISTONE DEACETYLASE INHIBITOR VALPROIC ACID FOR PATIENTS WITH GLIOBLASTOMA MULTIFORME","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakeridge Health","funders":"","keywords":"Temozolomide; Medicine; Valproic Acid; Internal medicine; Phases of clinical research; Radiation therapy; Oncology; Toxicity; Gastroenterology; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054038,0.000262096,0.0004413257,0.0001015204,0.0003478261,0.00001249779,0.0002296239,0.0001852777,0.000009506591],"category_scores_gemma":[0.0005515811,0.000182049,0.00009198234,0.0001201055,0.0004979751,0.00001091771,0.0002310621,0.0001922753,0.000003808165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001298904,"about_ca_system_score_gemma":0.0001434125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002324871,"about_ca_topic_score_gemma":0.0001837133,"domain_scores_codex":[0.9977828,0.0005327805,0.0004604072,0.0005643132,0.000291746,0.0003679694],"domain_scores_gemma":[0.998509,0.0002734357,0.0003409563,0.0004505751,0.0002848044,0.0001411836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01554304,0.003686718,0.0008504507,0.0000316702,0.0001047523,0.00000270987,0.001379877,0.0000178907,0.8936163,0.00001807794,0.003135325,0.08161317],"study_design_scores_gemma":[0.07149796,0.08546914,0.0003609527,0.000008172249,0.00006541894,0.0000182732,0.0001497379,0.0004747488,0.7206367,0.000005066342,0.1210499,0.0002638632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961241,0.0003480625,0.0001502484,0.0002571537,0.0003159016,0.002673294,0.00005427713,0.00001623898,0.00006065726],"genre_scores_gemma":[0.998728,0.00008041949,0.00007196566,0.0002024121,0.0002313989,0.0004869176,0.00008984444,0.00004824782,0.00006081218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1729796,"threshold_uncertainty_score":0.7423745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023374208187936,"score_gpt":0.3051719867733026,"score_spread":0.2949382446914232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}