{"id":"W2026356631","doi":"10.1093/neuonc/nou237.33","title":"AT-33A PHASE II STUDY OF CONCURRENT RADIATION THERAPY, TEMOZOLOMIDE AND THE HISTONE DEACETYLASE INHIBITOR VALPROIC ACID FOR PATIENTS WITH GLIOBLASTOMA MULTIFORME","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakeridge Health","funders":"","keywords":"Temozolomide; Medicine; Valproic Acid; Internal medicine; Phases of clinical research; Radiation therapy; Oncology; Toxicity; Gastroenterology; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001465475,0.001727645,0.002118019,0.0005245751,0.0004841021,0.0007835313,0.0009831303,0.001092961,0.003559514],"category_scores_gemma":[0.0005990221,0.0007434205,0.001421161,0.0005690064,0.001096099,0.0005903159,0.0003628686,0.002815771,0.0007896575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001213139,"about_ca_system_score_gemma":0.002858815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002495183,"about_ca_topic_score_gemma":0.005496456,"domain_scores_codex":[0.9995858,0.000210768,0.00001662491,0.00006580421,0.00003434137,0.00008663555],"domain_scores_gemma":[0.9993319,0.00006415026,0.0001030965,0.00003676245,0.00004258361,0.0004216035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7703103,0.07658495,0.01519144,0.0008935264,0.00173104,0.000515743,0.000473821,0.003346171,0.04977858,0.000449612,0.003268973,0.07745581],"study_design_scores_gemma":[0.3902077,0.5849279,0.01737611,0.00004881423,0.0005278105,0.0003997309,0.00006130669,0.0009373503,0.002663478,0.0001867165,0.002634698,0.00002829708],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948044,0.001652103,0.0003843402,0.0003470668,0.00006301681,0.0015663,0.0004893508,0.00004737997,0.0006461155],"genre_scores_gemma":[0.9908999,0.001739557,0.001627704,0.0004413781,0.000141323,0.002329443,0.001415561,0.00002122445,0.001383951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003559514,"threshold_uncertainty_score":0.0119077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023374208187936,"score_gpt":0.3051719867733026,"score_spread":0.2949382446914232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}