{"id":"W2026414440","doi":"10.1073/pnas.0305555101","title":"Ectopic expression of the homeobox gene <i>Cdx2</i> is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"CDX2; Ectopic expression; Myeloid leukemia; Homeobox; Cancer research; Fusion gene; Chromosomal translocation; Biology; Homeobox A1; Leukemia; ETV6; Myeloid; Bone marrow; Gene expression; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004478168,0.00009091042,0.0001302084,0.00004633236,0.0001006545,0.000006804934,0.0008963096,0.0001000218,0.000001044053],"category_scores_gemma":[0.00005069763,0.0000490341,0.0001194039,0.000204698,0.0004323672,0.00001766762,0.00017527,0.0001072797,5.307174e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003332027,"about_ca_system_score_gemma":0.0001259661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001827504,"about_ca_topic_score_gemma":0.000001644224,"domain_scores_codex":[0.998839,0.000005047226,0.0003480519,0.0001780962,0.0005056193,0.0001241562],"domain_scores_gemma":[0.9994628,0.0000120784,0.0003687603,0.00002671962,0.0001132116,0.00001644208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001394985,0.00002743731,0.0006732056,0.00003613502,0.00001097448,1.180114e-9,0.0003898105,0.01656244,0.9809732,0.001193305,0.00001991855,0.00009959414],"study_design_scores_gemma":[0.0002807349,0.00003885502,0.002344934,0.00006384271,0.00001071869,0.000002434113,0.0001334277,0.005050015,0.9816426,0.0103629,0.00001373328,0.00005581964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982616,0.0001288987,0.00003342818,0.000985059,0.00001069415,0.0001893103,0.00004402214,0.000001181856,0.0003458266],"genre_scores_gemma":[0.9983185,0.0002639132,0.001088384,0.0001834445,0.00002111868,0.000008625057,4.005418e-7,0.000004596148,0.0001110225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01151243,"threshold_uncertainty_score":0.1999553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01458093938702643,"score_gpt":0.2511836270383696,"score_spread":0.2366026876513431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}